13 citations,
December 2020 in “Dermatologic Therapy” Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
January 2016 in “SpringerBriefs in bioengineering” Genetic defects and UV radiation cause skin damage and aging.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
1 citations,
May 2023 in “Frontiers in medicine” Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.
November 2021 in “Austin therapeutics” Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.
126 citations,
August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
April 2017 in “Journal of dermatological science” Young mice's hair follicle stem cells are best for turning into heart muscle cells.
December 2022 in “Nature Communications” Bead-jet printing of stem cells improves muscle and hair regeneration.
13 citations,
March 2012 in “The Journal of Dermatology” Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
7 citations,
September 2013 in “Tissue engineering. Part A” Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
Curly hair may be caused by a muscle contraction, and muscle relaxants might help treat it.
29 citations,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
April 2017 in “Journal of dermatological science” Human hair follicles can produce stem cells that turn into heart muscle cells.
6 citations,
July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
December 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 4 citations,
January 2016 in “Methods in molecular biology” HAP stem cells can repair nerves, grow hair follicle nerves, and become heart muscle cells, making them useful for regenerative medicine.
77 citations,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
April 2023 in “Journal of Investigative Dermatology” Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
5 citations,
January 2023 in “Nature cell biology” A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
3 citations,
July 2019 in “Journal of Cosmetic Dermatology” New shampoo with tyramine hydrochloride reduces hair loss by making a small muscle in the hair follicle contract.
135 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
8 citations,
February 2021 in “Journal of Clinical Medicine” Hair follicle stem cells are promising for blood vessel formation and tissue repair.
2 citations,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
37 citations,
January 1987 in “Dermatology” Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
29 citations,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
25 citations,
October 2018 in “PloS one” Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
14 citations,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.