13 citations
,
September 2019 in “Scientific Reports” In this study, high levels of the protein Flii in mice were associated with worsened symptoms and inflammation in ulcerative colitis, suggesting Flii may inhibit mucosal healing.
3 citations
,
August 2024 in “Molecular Biology Reports” This study found that the lncRNA018392, responsive to melatonin, accelerates cell proliferation in cashmere goats by recruiting the transcription factor SPI1 to upregulate the nearby gene CSF1R, which may explain the molecular mechanisms of cashmere growth.
18 citations
,
July 2016 in “Journal of The American Academy of Dermatology” This study reported that both primary and secondary cutaneous follicle center lymphomas can present with atypical scalp or forehead lesions, leading to potential misdiagnosis as other skin conditions.
7 citations
,
January 2009 in “Biological & pharmaceutical bulletin” This study found that applying ferrous ferric chloride skin lotions to newborn mice stimulated skin cell proliferation and differentiation, increased hair growth, and inhibited alopecia-related hair loss.
December 2024 in “Tropical Journal of Natural Product Research” This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.
March 2021 in “Arrow - TU Dublin (Technological University Dublin)” This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.
April 2025 in “Journal of Investigative Dermatology” This study found that fibronectin supports hair follicle regeneration by influencing stem cell behavior through integrin-dependent mechanotransduction, highlighting its potential role in epidermal renewal.
April 2023 in “Research Square (Research Square)” This study found that melatonin-mediated lncRNA018392 accelerated cell proliferation and inhibited apoptosis in cashmere goat skin fibroblasts by upregulating the expression of the nearby gene CSF1R.
21 citations
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October 2013 in “Molecular Biology of the Cell” This study found that the protein CCN2 in dermal papilla cells is a physiologically relevant suppressor of hair follicle formation by destabilizing β-catenin, which may help maintain stem cell quiescence.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
19 citations
,
March 2022 in “Molecular therapy. Nucleic acids” This study found that silencing the circular RNA circNlgn in mice reduced doxorubicin-induced cardiofibrosis and cardiomyocyte apoptosis, suggesting potential therapeutic strategies for minimizing heart-related side effects in cancer treatment.
28 citations
,
June 1995 in “The Journal of Dermatology” This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
10 citations
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July 2019 in “Advances in Wound Care” This study suggests that Flightless I may inhibit the activation of epidermal stem cells during wound repair by disrupting Wnt/β-catenin signaling, potentially delaying wound reepithelialization.
4 citations
,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
25 citations
,
November 2017 in “Molecular Medicine Reports” This study found that PlncRNA‑1 may enhance the proliferation and differentiation of hair follicle stem cells by upregulating the TGF‑β1-mediated Wnt/β-catenin signaling pathway.
10 citations
,
June 2020 in “Journal of Cosmetic Dermatology” This study found a high prevalence of genital Lichen sclerosus and autoimmune comorbidities in patients with frontal fibrosing alopecia, suggesting a possible shared autoimmune process.
August 2009 in “Mechanisms of Development” 13 citations
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September 2012 in “Cell & tissue research/Cell and tissue research” In this study, researchers found that the pCLCA2 protein is expressed in specific areas of pig skin, but its role in skin structure or function remains unclear.
55 citations
,
November 2010 in “Journal of Allergy and Clinical Immunology” This study found that the TLR3 L412F genetic variant is associated with severe viral infections, especially CMV, and immune dysfunction in a subgroup of chronic mucocutaneous candidiasis patients.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that CTCF is crucial for proper skin and hair follicle development in mice, affecting keratinocyte differentiation and gene expression in keratin loci.
5 citations
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November 2005 This review discusses the applications of confocal laser scanning microscopy in visualizing fluorescent compounds within the skin, noting its potential for tracking drug carriers and enhancing penetration studies, but reports no new results.
April 2017 in “Journal of Investigative Dermatology” In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.
2 citations
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May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibronectin is crucial for hair follicle stem cell function and regeneration, with its deletion impairing regeneration but restoration by dermal injection of exogenous fibronectin.
33 citations
,
August 2000 in “Experimental Cell Research”
February 2024 in “Skin research and technology” The researchers in this study identified molecular mechanisms involved in frontal fibrosis alopecia, highlighting immune response and fatty acid metabolism, and developed a four-gene diagnostic model showing high accuracy in distinguishing affected individuals from controls.
September 2013 in “Hair transplant forum international” This abstract describes frontal fibrosing alopecia, a type of cicatricial alopecia identified in post-menopausal women, and reports no new clinical findings.
1 citations
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September 2021 in “CRC Press eBooks” This chapter reviews trichoscopic-pathologic correlations in Frontal Fibrosing Alopecia and reports no new clinical results; the authors discuss genetics, clinical patterns, and unusual variants associated with this condition.
2 citations
,
June 2024 in “Frontiers in Plant Science” This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.
July 2024 in “Journal of Investigative Dermatology” Linalool in fragrances may harm hair follicles and contribute to hair loss.
1 citations
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March 2020 in “QJM: An International Journal of Medicine” This study concluded that patients with chronic telogen effluvium had significantly lower levels of serum ferritin and lactoferrin compared to controls, suggesting potential benefits of supplementation.