May 2025 in “Journal of Clinical Images and Medical Case Reports” The study observed that patterned fibrosing alopecia, a type of scarring hair loss, appears in some patients after hair transplants, facelifts, and other surgical interventions, sharing features with lichen planopilaris and androgenetic alopecia.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this open-label study of post-menopausal women with frontal fibrosing alopecia, researchers found that 12 weeks of baricitinib monotherapy significantly reduced disease activity as measured by the Lichen Planopilaris Activity Index, improved patient-reported scalp hair growth, but showed no significant change in eyebrow growth.
25 citations
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June 2002 in “Steroids” This study examined 4-azasteroids using 13C-NMR spectroscopy, detailing the NMR spectrum assignments and reporting a new molecular complex of finasteride with dioxane.
July 2022 in “http://isrctn.com/” Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
26 citations
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January 2002 in “Advances in experimental medicine and biology” This article reviews the historical context of finasteride's development for BPH and its serendipitous discovery for hair growth, reporting no new research outcomes.
February 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride can cause skin reactions, so dermatologists should be aware.
3 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.
January 2017 in “Indian journal of sexually transmitted diseases and AIDS” Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.
July 2012 in “EFSA supporting publications” This technical report from the European Food Safety Authority responds to comments on its previous scientific opinion regarding a health claim about spermidine and hair growth, reporting no new experimental results.
July 2026 in “Free Radical Biology and Medicine” 1 citations
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March 2009 in “The Journal of Urology” This review discusses trials on therapies for benign prostatic hyperplasia and reports that combination treatment is more effective than monotherapy for symptom relief and slowing disease progression in men with moderate to severe symptoms and enlarged prostate glands.
January 2008 in “OhioLink ETD Center (Ohio Library and Information Network)” This review explores the potential of targeted topical drug delivery to hair follicles for treating conditions like acne and hair loss but reports no clinical results, emphasizing the need for more research.
April 2018 in “Journal of Investigative Dermatology” In a clinical phase I/IIa study, subcutaneous injections of the peptide FOL-005 increased hair growth by 8% and were safe for treating alopecia.
25 citations
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December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
2 citations
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May 2022 in “Advanced therapeutics” This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that Adapalene, Diosmin, and Azelastine have potential as multi-target drugs against Onchocerca volvulus and its endosymbiont, which might offer new therapeutic options for treating river blindness, but further research is needed to confirm their effectiveness.
January 2018 in “Digital Commons - PCOM (Philadelphia College of Osteopathic Medicine)” This systematic review of three randomized controlled trials found that topical eflornithine is an effective adjunctive therapy for reducing unwanted facial hair in women with hirsutism, with benefits lasting at least six months, although efficacy may diminish over time.
1 citations
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January 2002 in “European Urology Supplements” Tamsulosin works faster, but both drugs have similar effects after 6 months.
1 citations
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January 2020 in “Archives of Medical Research” Formononetin, found in red clover, may treat hair loss with fewer side effects.
September 2016 in “한국임상약학회지” In this study, ibuprofen, menthol, and cetirizine were found to potentially prevent or slow down damage to human dermal fibroblast cells caused by intermittent fever in early alopecia.
15 citations
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January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
December 1999 in “Evidence-based obstetrics and gynecology/Evidence-based obstetrics & gynecology” Flutamide worked better than finasteride for reducing excessive hair growth in women, but had more side effects.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
May 2022 in “The Journal of Sexual Medicine” In this retrospective study at Toyama University Hospital, amoxapine was reported to significantly improve semen volume, sperm concentration, and total sperm count in 17 men with ejaculatory disorders, with no observed side effects over an average of 13 months of therapy.
2 citations
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August 2011 in “Cochrane Database of Systematic Reviews”
This study found that both finasteride and low level laser therapy were similarly effective in improving hair regrowth for frontal pattern hair loss in men and women over a 3-month period.
1 citations
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January 2021 in “European Journal of Inflammation” In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.
24 citations
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November 2009 in “Pharmaceutical Development and Technology” This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.
1 citations
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November 2023 in “Journal of Innovations in Applied Pharmaceutical Science (JIAPS)” In this study, researchers developed a neem oil-based emulgel showcasing anti-dandruff properties with controlled dual release, observing formulation F5 providing a 65.27% release after 8 hours and the highest antifungal inhibition against Candida albicans.
1 citations
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April 2015 in “Drug research” This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.