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The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

The document says a skin condition called alopecia areata causes hair loss and stress, and is treated with strong skin creams, injections, or other therapies, but treatment success varies.

Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

Diphenylcyclopropenone treatment helps prevent hair loss relapse in alopecia areata patients.

Camouflaging agents like hair fibers and wigs significantly improve appearance and self-esteem for most hair loss patients.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Hair loss linked to higher heart disease risk in both men and women.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Recognizing specific features of African-American hair can help diagnose hair loss conditions.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Trichoscopy helps diagnose hair and scalp disorders in dark-skinned people by identifying unique patterns.

Seborrhoeic dermatitis may cause a condition called "seborrhoeic folliculitis," leading to chronic scalp inflammation and scarring hair loss.

Hair regrowth doesn't convert thin hairs to thick hairs, but increases overall hair density.

In the Middle Ages, European noblewomen intentionally removed forehead hair to be fashionable, showing how beauty standards can affect the perception of hair loss.

Plasma is better than Ringer's lactate for hair graft survival and growth after transplantation.

Postmenopausal women can experience hairline recession, affecting their quality of life, and more research is needed for treatments.

A woman's pelvic pain and bleeding led to finding and successfully treating a rare benign tumor in her reproductive system.

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.