A Histological and Clinical Evaluation of Plasma as a Graft Holding Solution and Its Efficacy in Hair Growth and Graft Survival
autologous plasma Ringer's lactate hair transplantation graft holding solution hair count hair density hair thickness hair graft survival hair shedding shock loss growth factors epithelialization neovascularization hair follicle stem cells plasma Ringer's solution hair transplant graft solution hair growth hair loss prevention stem cell stimulation
TLDR Plasma is better than Ringer's lactate for hair graft survival and growth after transplantation.
The study, conducted on six male patients aged between 25 and 40, compared autologous plasma to Ringer's lactate as a graft holding solution in hair transplantation. Results showed that grafts preserved in plasma had viable cells after 72 hours, unlike those in Ringer's lactate. Clinically, the plasma-treated side of the scalp had a significantly higher hair count and density, with 8.3 hairs and 27.5 grafts/cm² compared to 1.3 hairs and 4.4 grafts/cm² for the Ringer's lactate side, and also demonstrated higher hair thickness at 6 and 12 months. The study concluded that autologous plasma enhances hair graft survival and growth, prevents hair shedding and shock loss post-transplantation, due to growth factors in plasma that promote epithelialization, neovascularization, and stimulate hair follicle stem cells.
