3 citations,
June 2006 in “Expert Review of Dermatology”
The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stemcell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
Microneedling's effectiveness for hair regrowth is debated, with mixed results from studies. Some believe it helps with blood flow and scalp health, while others see it as largely ineffective.
Microneedling at depths greater than 0.6 mm may damage miniaturized hair follicles, with 0.5 mm showing better results for hair regrowth. Combining microneedling with minoxidil enhances absorption, but caution is advised to avoid damaging follicles.
Discussing a regimen to improve the user's hairline, with treatments proposed including minoxidil, rectal microneedling, IV drip of minoxidil, laser removal, PRP injection, topical minoxidil, divine protein shakes, stemcell injections, and keto shampoo.
Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stemcell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.