Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study observed that Ginseng and Albizia extracts, when used together, protected human dermal papilla cells from oxidative stress-induced senescence, and inhibited genes that suppress hair growth, indicating their potential in preventing age-related hair density reduction.

This study found weak epidemiological associations between male pattern baldness and coronary heart disease, but no significant genetic link, though specific loci shared risks with other conditions.

In this study, RNA-sequencing identified differentially expressed genes, including FGF5, FGFR1, and RRAS, that affect the hair follicle growth cycle in Inner Mongolian Cashmere goats.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

In this study, FGF5-knockout Dorper sheep generated using CRISPR/Cas9 showed increased fine-wool and active hair-follicle density, suggesting potential therapeutic applications for androgen alopecia.

This study found that STAT3 signaling is essential for initiating the hair growth phase but not involved in hair follicle development during the fetal period.

This exploratory pilot study reported that using a 2% Oleosome-FGF-2 fusion extract scalp serum twice daily for 84 days in women with telogen effluvium and brittle hair improved hair density, anagen/telogen ratio, hair shaft thickness, and scalp hydration compared to a placebo.

This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.

In this study, CD4+CD25+FoxP3+ Regulatory T cells were found to reduce TGF-b1 induced lung fibrosis and fibrocyte accumulation in mice, partly by suppressing fibroblast growth factor 9.

In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This study found differential expression of growth factors and cytokines in umbilical cord blood-derived platelet-rich plasma, with the highest concentrations observed in the B blood type, but also noted weak correlations with ABO blood groups, suggesting other influencing factors.

FGF18 controls hair growth rest phase.

This study found that recombinant keratinocyte growth factor (rKGF) stimulated hair growth and provided a protective effect against alopecia in murine models, suggesting its role in hair follicle development and regeneration.

This study found that FGF signaling is necessary for the initiation of feather placode development in chicken embryos, with FGF10 being implicated as an early dermal signal in the process.

This study found that FGF18 is crucial for regulating hair follicle rest and growth phases, as its absence in mice leads to a shorter resting phase and rapid hair cycling.

This study found that acupuncture and moxibustion therapy increased hair follicle growth and enhanced the expression of several growth factors in hair follicle cycles compared to a control group.

In this study, applying FGF-2-containing dalteparin/protamine nanoparticles to the scalp was associated with a significant increase in hair diameter over six months among participants with thin hair.

This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.

This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.

This study found that zebrafish with a mutation in the GDP-fucose biosynthesis gene exhibited enhanced and faster regeneration of mechanosensory hair cells, implicating the importance of this gene and Notch signalling regulation in hair cell regeneration mechanisms.

This study demonstrated that keratin extract can stimulate hair growth by inducing the anagen phase in telogenic mice.

In this study, researchers identified a number of differentially expressed genes that may influence wool growth in Aohan fine wool sheep, offering insight into the genetic regulation of wool quality and yield.

This study found that Ashwagandha-derived nanovesicles increased cell proliferation, angiogenesis, and growth factor expression in vitro, suggesting they may have potential as a plant-based alternative or complement to current therapies for hair and skin conditions.

This study found that recombinant human type XVII collagen (rhCOL17A1) promotes hair growth by activating the Wnt/β-catenin and SHH/GLI signaling pathways and increasing type XVII collagen expression, with significant effects observed in both cell and mouse models.

In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.

This study suggests that androgens enhance growth factor production in dermal fibroblasts, which in turn may alter keratinocyte differentiation and contribute to acne lesion formation.

In this study, a medicated hair growth tonic containing RJ extract increased hair counts, the proportion of anagen phase hairs, and scalp moisture in human trials, although the specific role of RJ in hair growth remains unclear due to other active ingredients.

This study found that arachidonic acid may promote hair growth by enhancing dermal papilla cell function and stimulating the anagen phase in C57BL/6 mice.

This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.