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Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

PCOS is a common hormonal disorder in women, often involving menstrual issues and increased diabetes risk, managed through lifestyle changes and targeted treatments.

19.7% of Afro-Caribbean women in Tobago have PCOS.

Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Tracnil™, a mix of myo-inositol, folic acid, and vitamin D3, safely reduced acne, improved excessive hair growth, and fixed irregular periods in overweight women with PCOS.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Skin problems like acne and excess hair in PCOS are common and linked to being overweight.

Skin creams that block male hormones may help with hair growth, hair loss, and acne.

Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.

Spironolactone may be effective for acne and other skin conditions and could be used more in treatment.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Auriculotherapy and Aslagh capsules are as effective as metformin for treating PCOS symptoms, with auriculotherapy slightly better for reducing hair growth.

Using only hyperandrogenism to diagnose PCOS can lead to overdiagnosis.

The document concludes that effectively managing PCOS requires a multifaceted approach.