Spironolactone in Dermatology: A Mini Review

    Jayakar Thomas, S Soundarya, Samantha Vaishnavi
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    Studysummary This review discusses the potential and varied uses of spironolactone in dermatological conditions such as acne, hidradenitis suppurativa, hirsutism, and female pattern androgenetic alopecia, emphasizing dosage, treatment recommendations, and adverse effects for practical clinical use.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Spironolactone, an aldosterone receptor antagonist with anti-androgenic effects, has shown potential in treating various dermatological conditions, although its use is not widely explored. It has been effective in treating acne, potentially serving as a first-line treatment. Other conditions where spironolactone has shown beneficial effects include hidradenitis suppurativa, hirsutism, and female pattern androgenetic alopecia. This review discusses the use of spironolactone in these common skin diseases, including dosage recommendations, treatment guidelines, and potential adverse effects, with the aim of incorporating this drug into daily clinical practice.
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