November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.
23 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews the pathophysiology, diagnosis, and treatment of female pattern hair loss, highlighting the importance of early medical intervention to arrest hair loss progression, but reports no new clinical results.
22 citations
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August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
July 2015 in “Journal of the Dermatology Nurses’ Association” This review covers the clinical presentation and challenges in treating frontal fibrosing alopecia in postmenopausal women and concludes that more research is needed to understand its etiology and develop effective treatments.
17 citations
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June 2016 in “Archives de Pédiatrie” This case report describes three pediatric cases of frontal fibrosing alopecia, a condition typically seen in postmenopausal women, including a unique instance involving female twins.
2 citations
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November 2018 in “Seminars in Cutaneous Medicine and Surgery” This source reviews treatments for female pattern hair loss and discusses the challenges in achieving effective regrowth, highlighting the need for combinations of topical, systemic, and interventional therapies.
This study found flutamide to be an effective long-term treatment for female pattern hair loss with improved alopecia scores and high compliance when using very low doses, though some potential for hepatic disorders was observed initially.
This abstract provides contact information for Dr. Ban Kamoona at the Medical University – Sofia and contains no research findings.
May 2025 in “International Ayurvedic Medical Journal” In this case study, a 38-year-old woman with alopecia areata experienced significant improvement in hair regrowth after treatment with rakthamokshana and a herbal lepa containing Shodita Kasisa and Triphala masi mixed with nilibringaraj taila.
February 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that administering 1000 mg/kg of LSFP significantly reduced serum FSH and LH levels and testicular index in male Wistar rats, while lower doses showed no such effect.
159 citations
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August 2010 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, hydroxychloroquine significantly reduced signs and symptoms of frontal fibrosing alopecia after 6 months of treatment, with maximal benefits observed within the first 6 months.
1 citations
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August 2017 in “Journal of food and nutrition research” This study found that the black bean-licorice-biotae folium extract may improve hair diameter, scalp moisture, and sebum secretion, although its effect on hair density was not significant.
49 citations
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November 2016 in “Frontiers in Pharmacology” This study found that over 26% of patients using Tripterygium wilfordii Hook F experienced adverse events, highlighting the need for better strategies to manage these risks.
Folicrex may help with hair growth and health but lacks clinical evidence.
September 2013 in “Hair transplant forum international” This abstract describes frontal fibrosing alopecia, a type of cicatricial alopecia identified in post-menopausal women, and reports no new clinical findings.
86 citations
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July 2002 in “Clinical and Experimental Dermatology” This review discusses female pattern hair loss, emphasizing its complex causes and the limited treatment options available, and reports no new clinical results.
8 citations
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April 2012 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that the herbal product containing Rosa multiflora roots extract improved hair density and thickness and significantly promoted hair growth in both mice and human patients after 16 weeks of treatment.
This study explored the molecular mechanisms by which Polygonum multiflorum may treat androgenic alopecia, suggesting it influences cell apoptosis and inflammation through specific pathways, with potential application value pending further testing.
January 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study reported significant improvements in female pattern hair loss through a combination therapy involving spironolactone, minoxidil, and an injectable treatment over 6 to 12 months, with 95-96% patient satisfaction and minimal complications such as slight pain and hair growth in undesirable areas.
14 citations
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November 2020 in “International Journal of Biological Macromolecules” This study found that Flammulina velutipes polysaccharides-derived scaffolds greatly enhanced wound healing and hair follicle regeneration in a rat model, particularly with the FPS/NaOH variant showing the best results.
1 citations
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May 2014 in “European Journal of Inflammation” This study found that a topical lotion containing minoxidil, hydrocortisone butyrate, and 17α-estradiol improved or stabilized frontal fibrosing alopecia in 35 out of 40 women over 36 months.
6 citations
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August 2012 in “PubMed” In this report, a 44-year-old woman with female pattern alopecia experienced significant hair regrowth after 3.5 months of oral finasteride, with no side effects, after not responding to topical minoxidil.
5 citations
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January 2013 in “Spatula DD - Peer Reviewed Journal on Complementary Medicine and Drug Discovery” This study found that a polyherbal formulation of Trigonella foenum-graecum and Butea monosperma significantly promoted hair growth and reduced DHT levels in a chemotherapy-induced alopecia model.
January 2020 in “Clinical Case Reports and Reviews” This study observed that the coexistence of Frontal Fibrosing Alopecia and lupus erythematosus in a patient may suggest a shared pathogenic background.
July 2022 in “L Endocrinologo” This case report describes a 77-year-old woman with female pattern hair loss and elevated testosterone levels, who showed no improvement with minoxidil and lacked adrenal tumors on imaging.
January 2017 in “Springer eBooks” Over 40% of postmenopausal women experience hair loss, with treatments aiming to stop further loss and possibly thicken hair.
12 citations
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July 2020 in “Actas Dermo-Sifiliográficas” This study found that facial papules and rosacea in patients with frontal fibrosing alopecia were linked to a greater need for oral treatment, with most cases involving postmenopausal women.
May 2019 in “The Journal of Sexual Medicine” This study found that among premenopausal women taking flibanserin, consuming wine with an evening meal may increase the risk of syncope and orthostatic hypotension-related adverse events compared to placebo.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
2 citations
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August 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study investigated the antioxidant and anti-inflammatory effects of the plant extract BLH308 and its potential to reduce hair loss, showing significant antioxidant activity in vitro.