7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
6 citations
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October 2021 in “Biomedical Research and Therapy” This meta-analysis found that alopecia areata patients had significantly higher serum levels of IL-6 and TNF-α compared to healthy subjects, indicating a potential role of these cytokines in the condition's pathogenesis.
18 citations
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February 2021 in “Archives of Dermatological Research” This study found that Physcion from Polygonum multiflorum may be an effective natural 5α-reductase inhibitor for treating androgenic alopecia by enhancing hair growth and improving follicle morphology in laboratory settings.
4 citations
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January 2019 in “Annals of Dermatology” In this study, researchers observed that RE-ORGA, a preparation from Korean herbs, may help alleviate androgenic alopecia by promoting human dermal papilla cell proliferation, reducing 5α-reductase enzyme levels, and displaying anti-inflammatory properties, suggesting potential regulation of androgen receptor sensitivity.
2 citations
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December 2017 in “Korean Journal of Medicinal Crop Science” This study found that 70% ethanol extract of Houttuynia cordata promoted hair growth in laboratory cell models, suggesting potential use in developing hair care products.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
45 citations
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September 2012 in “Life Sciences” This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.
115 citations
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September 2012 in “Experimental Dermatology” This article reviews the molecular mechanisms involved in androgenetic alopecia and the androgen's paradoxical role in hair growth, but reports no new experimental findings.
8 citations
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April 2012 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that the herbal product containing Rosa multiflora roots extract improved hair density and thickness and significantly promoted hair growth in both mice and human patients after 16 weeks of treatment.
51 citations
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January 2012 in “Annals of Dermatology” This review discusses characteristics of androgenetic alopecia in Asian patients and includes algorithmic management guidelines, but reports no new clinical findings.
173 citations
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September 2011 in “Journal of Investigative Dermatology” IL-6 contributes to hair loss by shortening the growth phase and causing hair follicles to regress.
126 citations
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January 2009 in “International Journal of Trichology” This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
112 citations
,
October 2005 in “Mayo Clinic Proceedings” This article reviews the clinical, psychological, and management aspects of androgenetic alopecia in men, stating that it can be effectively managed by generalist clinicians with pharmacotherapy and surgical advancements.
236 citations
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July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
51 citations
,
January 2001 in “Biological & Pharmaceutical Bulletin” This study found that the aqueous ethanol extract of Myricae Cortex demonstrated in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic effects in mouse and hamster models.
581 citations
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October 1998 in “Journal of The American Academy of Dermatology” In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.
22 citations
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January 1987 in “Dermatology” This article discusses the pathogenesis of androgenetic alopecia and suggests that genetic predisposition and androgen sensitivity, rather than endocrine disorders, drive hair follicle changes, with significant psychological implications for patients.