Fibrosing Alopecia in a Pattern Distribution in Two Brothers with Pili Multigemini
July 2015
TLDR Genetic factors might cause fibrosing alopecia linked to hair shaft abnormalities.
The document described a case study of two brothers, aged 25 and 26, who experienced increased hair loss over two years. They were diagnosed with a rare hair shaft defect known as pili multigemini, where multiple hairs grow from a single follicle, and fibrosing alopecia in a pattern distribution, a subtype of lichen planopilaris characterized by inflammation and fibrosis leading to hair loss in typical male or female pattern areas. The study suggested that the pili multigemini defect might have influenced the development of fibrosing alopecia in these cases.