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This study suggests that β-Catenin and extracellular matrix components interact in a regulatory loop to influence fibroblast behavior and wound repair properties in dermal tissue.

This study found that concentrated nanofat, used alone or with decellularized nanofat, may enhance hair growth in mice by activating dermal papilla cells and the anagen phase.

This study observed that NSPC predominantly differentiated into neurons when exposed to serum fractions with molecules under 100 kDa, particularly with biomaterial and fibronectin, in the presence of basic fibroblast growth factor.

This review discusses the development and advances in studying trichogenic dermal cells for hair follicle morphogenesis, summarizing methods, bioassays, and molecular markers, but reports no new research findings.

This study found that human dermal papilla cells are embedded in a basement membrane-like extracellular matrix, which is essential for their aggregation and function, as supported by evidence that Matrigel enhances dermal papilla cohesion and gene expression compared to collagen I, which promotes cell dispersion.

This study found that human dermal papilla cells are surrounded by a basement membrane-like extracellular matrix, which maintains their aggregated structure without strong cell‒cell contacts.

This study suggests that incorporating matrisomal components into biomaterials could enhance skin wound healing in mammals that do not naturally regenerate tissues like the axolotl and Acomys.

This study found that extracellular matrix components influenced the adhesion and proliferation of stem cells from various sources differently, with only laminin reducing proliferation in certain mesenchymal stem cells.

This study highlights the distinct distribution patterns of extracellular matrix components in the scalp skin of male and female androgenetic alopecia patients, with increased elastin staining intensity observed in male cases.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This review discusses the mechanisms of wound healing and excessive scarring, highlighting the importance of understanding these processes for developing new therapies to prevent fibrotic scarring in large skin wounds.

In this study, around 1% of proteins in skin fibroblasts significantly changed in response to reductive stress, affecting collagens and MAPK signaling pathways.

In this study, researchers demonstrated that fibroblasts derived from human embryonic stem cells can be used to create tissue-engineered dermal substitutes, effectively repairing mouse skin wounds within 20 days, highlighting a promising method for clinical applications in skin repair.

In this study, researchers identified that upon tissue injury in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state with SOX11 and SOX4 playing a central role in modulating epidermal development and cell migration genes.

This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.

This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.

This review discusses the unique capacity of fetal skin to heal wounds without scarring and notes that while many factors have been identified, the complete mechanism of fetal wound healing remains unclear.

This study suggests that human skin contains distinct fibroblast subsets with unique expression profiles and functions, which can be isolated to investigate their role in skin pathogenesis.

This study identifies cartilage oligomeric matrix protein (COMP) as a key extracellular matrix component in human hair follicle cycling, potentially regulated by TGFβ signaling, and suggests its importance in normal hair follicle biology.

In this study, researchers detailed how hair follicles regenerate after microsurgical amputation, observing a wound reaction involving dynamic dermal-epidermal interactions and changes in extracellular matrix components.

Epithelial cell growth in rat hair follicles needs contact with mesenchymal cells through the extracellular matrix.

This study observed that cultured dermal papilla cells showed distinct functional properties from dermal fibroblasts, including lower proliferation rates, higher adhesion to collagen type IV, and different cell-matrix interactions.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This article discusses the distribution of extracellular matrix molecules in human hair follicles and reports no new results.

This study found that generating pluripotent stem cell-derived skin organoids in a 3D bioprinted hydrogel device improved keratinocyte differentiation and hair follicle formation while reducing necrosis.

This review focuses on hydrogel microsphere-mediated strategies to improve organoid culture by addressing deficiencies in extracellular matrix organization, potentially enhancing the physiological accuracy and clinical translatability of osteomuscular in vitro models as reported in this study.

This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.

This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.

This study identified lymphatic vessels as crucial components of the hair follicle stem cell niche, coordinating connections and contributing to hair follicle regeneration in mice.