April 2018 in “Journal of Ayurvedic and herbal medicine” Computational methods can speed up and improve the development and safety of herbal drugs.
30 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
19 citations,
June 2022 in “Molecular therapy. Nucleic acids” A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
22 citations,
August 2021 in “Frontiers in medicine” Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
182 citations,
August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
18 citations,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
7 citations,
May 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Different ligands change the shape of the TRPV3 ion channel in unique ways.
158 citations,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
2 citations,
January 2019 in “Biomecánica” Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.
3 citations,
January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
11 citations,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
4 citations,
January 2018 in “Journal of dermatology & dermatologic surgery” There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.
17 citations,
February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
20 citations,
March 2013 in “Journal of Lipid Research” The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
1 citations,
January 2023 in “Aesthetic surgery journal” Facial plastic surgeries and aesthetic procedures are becoming more popular in India, with a preference for non-surgical options and effective treatments for facial enhancement and hair loss.
March 2024 in “International journal of molecular sciences” Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.
36 citations,
June 2014 in “Experimental Neurology” Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
450 citations,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
1 citations,
November 2021 in “Biomedicines” Understanding how acne develops in different diseases could lead to new treatments.
26 citations,
January 1994 in “Clinics in Dermatology” Artificial skin is improving wound healing and shows potential for treating different types of wounds.
75 citations,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
6 citations,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
11 citations,
January 2004 in “Exogenous dermatology” Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.
31 citations,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
57 citations,
July 2005 in “Genetics” Key genes are crucial for Drosophila wing development and could be insecticide targets.