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A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

Common variants in the Trichohyalin gene are linked to straight hair in Europeans.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Dlx3 is essential for hair growth and regeneration.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

FGF5 gene mutations cause long hair in domestic cats.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

Notch signaling is essential for healthy skin and hair follicle maintenance.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Vitamin D and its receptor may help prevent skin cancer.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.