2 citations
,
April 2019 in “Journal of Internal Medicine” Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
January 2024 in “Wiadomości Lekarskie” This study highlights the role of innate immunity and purinergic signaling in regulating hematopoiesis and hematopoietic stem/progenitor cell specification. The researchers observed that these ancient pathways operate both paracrinally and autocrinally within HSPCs, maintaining their developmental function throughout evolution.
February 2026 in “International Journal of Science and Research (IJSR)” This study reports that salmon DNA is emerging as a promising ingredient in skincare and aesthetics, with research highlighting its potential to improve skin health and appearance through anti-aging, hydration, and regenerative properties.
3 citations
,
September 2014 in “SpringerPlus” This study suggests that hair loss was a metabolic adaptation allowing hominids to evolve larger brains by alleviating dietary restrictions on essential amino acids for hair and brain development.
1 citations
,
October 2013 This chapter discusses stem cell activity in feather and hair follicles, emphasizing how stem cells maintain their population by cycling between quiescence and activation in specialized niches but reports no new results.
November 2022 in “Research Square (Research Square)” This study found that keratin-associated proteins related to metallothionein and occludin appear in various animals, suggesting they may have roles beyond hair characteristics and were later adapted for hair production.
1 citations
,
November 2011 in “Revista Médica Clínica Las Condes” This review explores the physiopathology and treatment of hair and alopecia and reports no new experimental findings.
January 2025 in “Nature Communications” Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.
August 2024 in “Cosmoderma” 3D-printed hair follicles could revolutionize hair loss treatments by providing unlimited hair grafts.
38 citations
,
July 2004 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” This article discusses a hypothesis on the development and evolution of scales, hairs, and feathers from fish to amniotes, based on regions of dermo-epidermal interactions in skin, but reports no new findings.
232 citations
,
January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
152 citations
,
January 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
85 citations
,
October 2006 in “Current opinion in cell biology” This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
32 citations
,
October 1985 in “Annals of the New York Academy of Sciences” This review discusses the current understanding of genes coding for hair and avian keratins, highlighting gene structure and protein sequences, but reports no new experimental findings.
11 citations
,
January 1997 in “Journal of Dermatological Science” This study identified a human sequence likely coding for a new ultra-high sulphur protein, which may aid in understanding hair differentiation and the molecular basis of human trichothiodystrophy.
9 citations
,
January 2014 in “Medical Hypotheses” This article discusses the hypothesis that mechanisms driving androgenic alopecia may reduce the risk and proliferation of prostate cancer by increasing prostaglandin D2 levels but presents no new clinical findings.
8 citations
,
March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
August 2026 in “Journal of Genome Biotechnology and Genetics” This review found that while forensic DNA phenotyping and health applications for pigmentation genetics show potential, factors like phenotype definition and population diversity present challenges to accurate genotype-to-appearance predictions.
27 citations
,
May 2011 in “Journal of Investigative Dermatology” TCHHL1 is a protein important for hair growth, found in hair follicles.
1 citations
,
January 2025 in “Updates in clinical dermatology” New treatments for vitiligo, including the first FDA-approved option, are improving patient care and quality of life.
418 citations
,
January 2018 in “Journal of Investigative Dermatology” This study identified at least four distinct fibroblast populations in adult human skin, each with unique functional properties, suggesting potential therapeutic applications for wound healing and fibrosis-related diseases.
188 citations
,
January 2003 in “Recent results in cancer research/Recent Results in Cancer Research” This review explores the biological functions of vitamin D, highlighting how deficiency may increase the risk of various diseases, but reports no new clinical results.
92 citations
,
September 2015 in “Journal of Lipid Research” This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.
68 citations
,
November 2018 in “Molecular Biology and Evolution” This study found that keratin genes in the epidermis of aquatic mammals like cetaceans have evolved to replace stress-inducible keratins K1 and K10 with constitutively expressed K6 and K17, suggesting adaptations to their environment.
45 citations
,
April 2009 in “Journal of anatomy” This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.
40 citations
,
September 2010 in “Journal of Biological Chemistry” This study found that keratin K80, structurally similar to hair keratins, is broadly expressed in various epithelial tissues and is involved in intermediate filament formation with multiple type I partners.
38 citations
,
October 1988 in “Clinics in Dermatology” This article reviews the historical development of understanding the hair growth cycle, particularly anagen, catagen, and telogen phases, and reports no new clinical findings.
24 citations
,
November 1997 in “Journal of Biological Chemistry” This study found that genes encoding mouse high-glycine/tyrosine proteins show distinct spatial and temporal expression patterns in hair follicles, suggesting diverse protein distribution during hair growth cycles.
20 citations
,
May 2013 in “International Journal of Molecular Medicine” This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.
20 citations
,
September 2004 in “Journal of Anatomy” This study suggests that the structure and function of the inner root sheath in mammalian hair may have evolved from simpler forms seen in monotremes, aiding in hair exit without damaging the epidermis.