Comparative Aspects of the Inner Root Sheath in Adult and Developing Hairs of Mammals in Relation to the Evolution of Hairs

    September 2004 in “ Journal of Anatomy ”
    Lorenzo Alibardi
    Studysummary This study suggests that the structure and function of the inner root sheath in mammalian hair may have evolved from simpler forms seen in monotremes, aiding in hair exit without damaging the epidermis.
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    Research cited in this study 19

    1. Trichohyalin Mechanically Strengthens the Hair Follicle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    2. Distribution of Keratin and Associated Proteins in the Epidermis of Monotreme, Marsupial, and Placental Mammals Journal of Morphology · 2003
    3. A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2002
    4. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    5. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    6. A Unique Type I Keratin Intermediate Filament Gene Family Is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles Journal of Investigative Dermatology · 2001
    7. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    8. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    9. The Fate of Trichohyalin Journal of biological chemistry/˜The œJournal of biological chemistry · 1997
    10. Hair Follicle Companion Layer: Reacquainting an Old Friend ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1995
    11. Existence of Trichohyalin-Keratohyalin Hybrid Granules: Co-Localization of Two Major Intermediate Filament-Associated Proteins in Non-Follicular Epithelia Differentiation · 1994
    12. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993
    13. Changes in Fibronectin, Laminin, and Type IV Collagen Distribution Relate to Basement Membrane Restructuring During the Rat Vibrissa Follicle Hair Growth Cycle PubMed · 1992
    14. The Secret Life of the Hair Follicle Trends in genetics · 1992
    15. Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1991
    16. Structure and Biochemistry of Mammalian Hard Keratin Electron Microscopy Reviews · 1991
    17. Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    18. Genes for Hair and Avian Keratins Annals of the New York Academy of Sciences · 1985
    19. The Cytology and Cytochemistry of the Wool Follicle International review of cytology · 1979

    Related research 5

    1. TRPV3 Gain-of-Function Mutation Impairs Differentiation of Hair Follicle Inner Root Sheath ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    2. Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    3. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981