August 2024 in “Nutrition Bulletin” This editorial examines how GLP-1 receptor agonists, providing significant weight loss and cardiovascular benefits, can be integrated into a comprehensive obesity treatment alongside diet and lifestyle changes, but highlights the need for further guidance on their real-world application and multidisciplinary care.
January 2024 in “Clinical dermatology open access journal” This paper reviews existing research on the cosmetic benefits of hemp-derived cannabinoids for skin and hair, highlighting their unique mechanisms of action, while discussing formulation, legal, and regulatory challenges associated with using these compounds in cosmetic products.
April 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study found that pharmacists using the EVInews database for self-medication information achieved significantly higher quality scores compared to those using other web-based sources.
Some TikTok hair loss remedies like rosemary oil, onion juice, and garlic gel show promise, but more research is needed and they might delay proper treatment.
September 2018 in “Fertility and Sterility” This study found that in women with PCOS, lipid-induced NFκB activation is independent of obesity and exhibited evidence of LPS tolerance in combination with obesity and hyperandrogenism.
This study found that plucked hair follicles exhibited a higher growth rate than conventional one-hair micrografts in vitro, suggesting they may be a less invasive alternative for hair transplantation.
April 2004 in “AWHONN Lifelines” Hormonal contraception likely doesn't cause significant weight gain.
June 2021 in “Journal of Aesthetic Nursing” This review discusses the use of platelet-rich plasma for hair loss treatment and provides insights from 8 years of clinical experience, but reports no new clinical results.
253 citations
,
March 2006 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.
151 citations
,
May 2014 in “American Journal of Clinical Dermatology” This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
140 citations
,
January 2021 in “Journal of the International Society of Sports Nutrition” This source reports that while creatine supplementation is popular for improving muscle mass and performance, questions about its efficacy and safety persist. An expert team is reviewing literature to address concerns like water retention, renal effects, and its benefits across different populations and uses.
115 citations
,
October 2003 in “Journal of Neuroscience” This study found no evidence supporting the hypothesis that Aβ afferents sprout into the superficial laminas of the spinal cord after nerve injury in rats.
72 citations
,
July 2014 in “American journal of clinical dermatology” This review analyzed randomized controlled trials on alopecia areata treatment and found that while several treatments showed effectiveness, most studies had limitations affecting their interpretability.
71 citations
,
March 2009 in “Seminars in cutaneous medicine and surgery” This review discusses evidence for alopecia areata treatments, highlighting their ability to stimulate hair growth but noting limited data on long-term efficacy and impact on quality of life.
55 citations
,
January 2004 in “The International Journal of Developmental Biology” This study reports that corneal transient amplifying cells can be reprogrammed into epidermal cells capable of forming hair follicles in response to embryonic dermis signals.
47 citations
,
September 2004 in “Journal of Biological Chemistry” This study provides evidence supporting a regulatory relationship between the transcriptional regulator Hoxc13 and Krtap16 genes, which are crucial for proper hair growth in mice.
36 citations
,
October 2019 in “Cell Proliferation” This study reported that tryptanthrin, a compound found in indigo naturalis, effectively suppresses non-melanoma skin cancer in mice by reducing inflammation, inhibiting cell proliferation, and blocking specific signaling pathways associated with tumor growth.
36 citations
,
December 2016 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated the hair pull test and found that normal values should be reduced to two hairs or fewer, with no significant impact from hair washing, brushing, or lifestyle factors such as hair texture and medication use.
35 citations
,
December 2020 in “International Journal of Molecular Sciences” This review examines the mixed evidence on mast cells as regulators of skin fibrosis and highlights existing gaps in the scientific understanding, reporting no new experimental results.
33 citations
,
April 2021 in “Journal of Dermatological Treatment” New ways to treat acne are being discovered.
29 citations
,
January 2018 in “International Journal of Trichology” This meta-analysis reported that platelet-rich plasma injections for androgenetic alopecia may increase hair number and thickness locally, but further studies are needed to establish their overall effectiveness.
29 citations
,
August 2017 in “Skin appendage disorders” This study found that IGF-1 likely plays a crucial role in regulating hair growth and alopecia, with balding scalp follicles secreting less IGF-1 than nonbalding counterparts.
27 citations
,
October 2003 in “Journal of the American Academy of Dermatology” This case report describes white piedra infection of the scalp hair with a synergistic bacterial infection in two US native sisters, highlighting its relevance in diagnosing scalp hair concretions despite its rarity in North America.
26 citations
,
October 2018 in “International journal of osteoarchaeology” This study found evidence of fern consumption in the medieval population of the Balearic Islands by identifying fern sporangium annuli in dental calculus, suggesting potential medicinal usage.
25 citations
,
September 2005 in “International Journal of Developmental Neuroscience” This study found that in rats, morphine exposure may increase 5alpha-reductase activity in the CNS, leading to decreased testosterone levels, an effect blocked by finasteride.
25 citations
,
October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study characterized the mouse profilaggrin gene, finding it structurally identical to its human counterpart, and noted differences in protein-coding regions that could impact epidermal differentiation.
17 citations
,
October 2017 in “Journal of cosmetic and laser therapy” This literature review reports that laser-assisted hair removal may improve psychological well-being in women with PCOS, emphasizing its effectiveness and safety when conducted by trained professionals.
13 citations
,
June 2006 in “Brain Research” Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
12 citations
,
May 2024 in “Indian Dermatology Online Journal” This study reviewed the role of probiotics in dermatological disorders and suggests they may help treat or prevent inflammatory skin conditions by modulating the microbiota, potentially reducing the need for steroids and antibiotics, though further research is needed to confirm efficacy and safety.
12 citations
,
October 2013 in “British Journal of Dermatology” This meeting report provides an overview of recent evidence on vitiligo treatments, indicating a lack of standardized outcome measures and emphasizing the need for more consistent clinical trials.