This protocol outlines a planned systematic review on the effectiveness and safety of non-conventional treatments for male androgenetic alopecia, reporting no new results.
March 2021 in “British Journal of Dermatology” This study using a humanized mouse model of androgenetic alopecia suggests that platelet-rich plasma may promote hair regrowth and improve hair characteristics in vivo.
120 citations
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April 2009 in “Food Chemistry” This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.
99 citations
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May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
87 citations
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May 2018 in “Scientific Reports” This study found that in healthy men, higher levels of free testosterone were associated with a stronger immune response to the influenza vaccine, suggesting androgens may function as immunomodulators rather than strict immunosuppressants.
56 citations
,
November 2016 in “Aesthetic surgery journal” This review discusses the varied use and inconsistent reporting of platelet rich plasma in aesthetic surgery, finding that current studies lack consistent methodologies and objective evidence, and reports no new clinical results.
40 citations
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January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
20 citations
,
February 1977 in “The anatomical record” This study found that excess vitamin A in organ cultures of mouse embryos led to significant changes in epidermis and hair follicles, altering morphogenesis and polysaccharide distribution.
14 citations
,
August 2010 in “Journal of Investigative Dermatology” HPV does not cause aggressive cancer in RDEB patients.
10 citations
,
June 2011 in “Movement Disorders” THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
9 citations
,
June 2017 in “Pharmacological Reports” This study found that ATP-sensitive potassium channels may play a role in chloroquine-induced itching in mice, as channel openers reduced scratching behavior while a blocker reversed these effects.
7 citations
,
March 2018 in “Experimental Dermatology” This study found no evidence of increased keratinocyte proliferation in acne vulgaris, suggesting that other mechanisms may be responsible for hyperkeratinization in acne pathogenesis.
7 citations
,
January 2017 in “Skin Pharmacology and Physiology” This study provides scientific backing for the use of ECOHAIR® spray in patients with noncicatricial alopecia, showing improvements in hair volume, appearance, growth, and reduced hair loss over a 3-month period, with no local adverse effects reported.
6 citations
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July 2023 in “Diabetology” This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.
6 citations
,
September 2018 in “ACS applied bio materials” This study provides conclusive evidence of exogenous calcium fatty acid deposits forming between the cuticle layers in hair, affecting its optical and mechanical properties.
5 citations
,
September 2017 in “Journal of Cosmetic Dermatology” This review of clinical data found that an oral marine supplement increased hair growth and thickness while reducing hair loss in women and men with thinning hair, suggesting it is a safe and effective treatment.
4 citations
,
June 2024 in “Journal of pharmacopuncture” This review compiles current experimental research on Alzheimer's and cognitive impairment models, highlighting the potential of *Polygonum multiflorum* for treating neurological disorders and suggesting a foundation for future clinical trials.
4 citations
,
November 2023 in “Acta obstetricia et gynecologica Scandinavica” In this guideline update, researchers emphasized refining diagnostic criteria for polycystic ovary syndrome using ultrasound or hormone levels, while highlighting a healthy lifestyle's importance without specific diet recommendations, and reviewed treatments with a focus on comorbidities and pregnancies from a Nordic standpoint.
3 citations
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April 2025 in “Journal of Clinical Epidemiology” This study found that non-blinded assessors in randomized clinical trials exaggerated the effects of experimental interventions by about 29% compared to blinded assessors, indicating a significant potential for observer bias in treatment evaluations.
3 citations
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June 2022 in “Journal of the European Academy of Dermatology and Venereology” This study describes the presence of SARS-CoV-2 in hair follicles from a patient with early-onset post-COVID hair loss, suggesting a potential direct impact of the virus on hair physiology.
3 citations
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November 2021 in “Frontiers in Medicine” This study found that androgenetic alopecia can affect the occipital region in men with advanced stages of the condition.
3 citations
,
September 2018 in “Journal of Structural Biology” Oxidized trichocyte keratin has a helical dislocation in its structure.
February 2026 in “Editora Pasteur eBooks” This abstract does not report specific research results but introduces a book focusing on the intersection of endocrinology and aesthetic medicine and its growing importance in contemporary clinical practice.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report concludes that early-onset alopecia areata does not independently predict poorer long-term outcomes, with prognosis more strongly influenced by baseline severity and treatment response.
May 2026 in “Frontiers in Reproductive Health” This narrative review reported that a variety of lifestyle-based interventions, such as specific dietary changes and physical activity, along with adjunctive therapies, have potential benefits in managing metabolic and hormonal outcomes in women with PCOS, although the variable study quality suggests further research is needed.
April 2026 in “Open MIND” This case report suggests that Post-Finasteride Syndrome may involve a sustained imbalance in gut bacteria, with fermenting and hydrogen sulphide-producing bacteria disrupting hormone and mitochondrial functions.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report proposes that Post-Finasteride Syndrome might be sustained by specific microbes in the small intestine affecting hormone excretion and mitochondrial function, warranting further investigation in a larger cohort.
JAK inhibitors effectively regrow hair in alopecia areata but hair loss often returns after stopping treatment.
July 2025 in “Journal of Investigative Dermatology” Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.
April 2025 in “International Journal of Homoeopathic Sciences” In this study, individualized homoeopathic treatment with Natrum muriaticum resulted in a significant improvement in a 16-year-old girl with alopecia areata, showcasing a notable outcome at the Govt. Homoeopathic Medical College in Trivandrum.