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Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.

This study found that low-dose tamoxifen may effectively treat painful gynecomastia in patients receiving flutamide and finasteride for advanced prostate cancer.

This study found that novel androgen antagonists incorporating a carborane moiety showed anti-androgenic activity comparable to flutamide in a laboratory setting.

This study found that combining Flutamide and an LHRH agonist in adult male rats effectively inhibited prostatic growth and reduced androgen-sensitive prostatic activity markers to levels similar to castrated rats.

This review discusses the use of antiandrogens for various conditions like prostate cancer and highlights their potential benefits in remission rates and symptom improvement, but it reports no new clinical results.

This review discusses the complex links between polycystic ovary syndrome, insulin resistance, and potential metabolic risks starting in adolescence, noting the need for early screening and treatment but reports no new clinical results.

This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.

This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.

This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.

This review examines hormonal therapies for acne in females, noting their effectiveness and encouraging further study and use to reduce antibiotic reliance, but it reports no new results.

This study found that two synthesized androst-4-ene-3-one derivatives, 6f and 6g, exhibited stronger anti-proliferative effects than common drugs on prostate cancer cell lines, with low toxicity to rat cells.

This review found no evidence that medications used to manage PCOS add to cardiovascular risk or prevent diabetes onset, although metformin may help prevent gestational diabetes in these patients.

This article reviews the use of anti-androgens for dermatological conditions linked to androgen involvement and reports encouraging clinical experiences in females, with use in males limited to specific conditions due to toxicity concerns.

This review discusses the etiology, diagnosis, and management of polycystic ovary syndrome and reports no new clinical findings.

The article was retracted due to data integrity issues.

This review provides a comprehensive examination of the causes and treatments for hirsutism in women, highlighting the role of pharmacological therapies and novel nanotechnology-based methods in improving patient quality of life.

This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.

This study found that spironolactone significantly reduced hirsutism scores in women with idiopathic hirsutism compared to finasteride and cyproterone acetate but showed no significant difference among women with PCOS compared to flutamide and finasteride, and it was well tolerated overall.

This review examines treatment options for PCOS, highlighting the importance of managing symptoms and patient counseling, and reports no new clinical results.

This review discusses antiandrogen therapy for polycystic ovary syndrome, focusing on strategies to manage excessive androgen secretion, but it reports no new clinical results.

This study found that flutamide-induced liver toxicity in prostate cancer patients was very rare, occurring in only 0.18% of cases with clinical manifestations, and symptoms resolved after discontinuing the drug.

This review discusses the use of antiandrogens like flutamide and its derivatives in prostate cancer treatment and highlights the need for next-generation antiandrogens for improved efficacy; it reports no new clinical results.

This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.

This article reviews the diagnosis and treatment approaches for cutaneous manifestations of PCOS, reporting on various treatment options without presenting new clinical results.

This study found that both finasteride and flutamide effectively reduce hirsutism in women with polycystic ovary syndrome or idiopathic hirsutism, but flutamide was more effective.

This study concluded that finasteride, cyproterone acetate, and flutamide were similarly effective at reducing hirsutism in women, though they acted through different mechanisms.

This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.

This study found that long-term flutamide treatment reduced hair loss in women with female pattern hair loss, but liver-related dropouts were minimized at a very low dose of 62.5 mg/day.