9 citations
,
August 2021 in “International journal of molecular sciences” This study found that loss of epidermal PPARγ in mice altered the expression of many genes related to skin inflammation, keratinization, and sebaceous gland function, indicating its key role in maintaining skin homeostasis.
8 citations
,
May 2023 in “Cureus” In this case report, a 64-year-old woman developed alopecia areata after starting the IL-17A inhibitor secukinumab for psoriasis, highlighting a potential rare side effect of this treatment, with only three similar cases reported in the literature.
8 citations
,
February 2017 in “International journal of molecular sciences” This study found that the natural extract e-CAF promotes the proliferation and migration of human hair dermal papilla cells in vitro, suggesting potential benefits for skin regeneration and tissue repair.
8 citations
,
June 2016 in “Journal of Pediatric Orthopaedics B” This paper presents two cases of hair tourniquet syndrome and suggests washing baby socks inside out as a potential preventative measure.
8 citations
,
April 2016 in “Experimental dermatology” This study found that the immune-competent B6. Cg‐Tyr c−2J Hr hr /J congenic mouse line had a more pronounced delayed sunburn response and different proliferative skin reactions to UV exposure compared to SKH 1 mice.
6 citations
,
March 2019 in “International Journal of Molecular Medicine” This study found that finasteride-loaded microspheres effectively treated androgenic alopecia in a mouse model, showing similar hair growth effects to orally-administered finasteride.
6 citations
,
November 2015 in “JAMA” This study found that oral contraceptive pills improve mild hirsutism, while flutamide and spironolactone are beneficial for more severe cases, but other therapies show inconsistent or no benefit.
5 citations
,
January 2024 in “Journal of the American Academy of Dermatology” This study provided 18 evidence-based recommendations for managing acne vulgaris, strongly endorsing treatments like benzoyl peroxide, topical retinoids, and oral isotretinoin for severe cases, and issued conditional recommendations for therapies like salicylic acid and spironolactone, while offering good practice statements on combining treatment methods.
5 citations
,
December 2020 in “Wound Repair and Regeneration” This review discusses the challenges and perspectives of using platelet-rich plasma in burn and wound management, noting that current variability in its composition and application prevents clear conclusions on its effectiveness.
5 citations
,
April 2014 in “International Journal of Pediatric Endocrinology” This study concluded that prepubertal girls with hypertrichosis have androgen receptors with enhanced sensitivity, which may contribute to their increased body hair growth.
4 citations
,
May 2025 in “Clinical & Experimental Allergy” This study confirmed omalizumab's safety but noted that hair loss was more prevalent than previously reported, with side effects influencing treatment decisions especially in patients with reduced medication effectiveness.
4 citations
,
January 2025 in “The Journal of Cell Biology” This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.
3 citations
,
May 2021 in “Dermatologic Clinics” This article reviews global insights on how COVID-19 has transformed the practice of dermatology, but it reports no new clinical results.
3 citations
,
March 2018 in “Journal of Continuing Education in Nursing” This study found that a continuing education program significantly improved rural nurse practitioners' knowledge about assessing, diagnosing, and managing PCOS.
3 citations
,
February 2018 in “Vigilância Sanitária em Debate” This review discusses the characteristics and potential clinical applications of platelet-rich plasma in Brazil, emphasizing the need for standardized protocols and regulatory oversight to ensure safety and efficacy.
3 citations
,
January 2014 This study concluded that a green tea extract hair tonic was stable, promoted more hair growth than 2.5% minoxidil, and did not cause skin irritation.
This study suggests that exogenous retinoic acid can alter the morphogenesis pathway of developing skin appendages when applied during the placodal stage, leading to changes like feather formation in atypical regions of chick embryos.
2 citations
,
April 2024 in “European Journal of Dermatology” In this study, researchers analyzed data from Spain to find that alopecia areata is more prevalent in adults, with a point prevalence of 0.44% in 2021; they also noted significant healthcare costs and comorbidities, highlighting an unmet treatment need given limited systemic treatment use.
2 citations
,
August 2023 in “Autophagy” In this study, researchers found that keratinocyte-specific deletion of the autophagy mediator Atg16l1 in mice heightened skin inflammation and cancer responses, altered hair follicle stem cell activity, and sensitized keratinocytes to cell death.
2 citations
,
August 2021 in “Journal of Turkish sleep medicine” In this study, researchers found that women with polycystic ovary syndrome were more likely to experience sleep disorders compared to healthy controls, suggesting a potential link between the syndrome and sleep issues.
2 citations
,
May 2018 in “Diagnosis” This case report presents a rare instance of an ovarian steroid cell tumor in a 68-year-old female with virilism, which normalized androgen levels following surgical removal.
1 citations
,
December 2025 in “Baylor University Medical Center Proceedings” Leuprolide may better manage cholesterol and blood pressure in PCOS than spironolactone.
1 citations
,
December 2022 in “Life” This review systematically analyzed evidence on treatment options for erosive pustular dermatosis, finding that while potent topical steroids like clobetasol propionate can be effective, recurrence is common, and more robust studies are necessary for stronger recommendations.
1 citations
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October 2022 in “Current Dermatology Reports” This review discusses various skin reactions after SARS-CoV-2 infection and COVID-19 vaccination, noting a higher incidence with mRNA vaccines than adenovirus vector vaccines, and reports no new clinical results.
1 citations
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August 2022 in “Biomedicines” This review assesses the potential of dutasteride as a promising treatment for ALS due to its reported neuroprotective, antioxidant, and anti-inflammatory effects, but emphasizes that clinical studies are needed for confirmation.
1 citations
,
September 2017 in “Journal of Investigative Dermatology” Hair loss is more common in summer and fall.
1 citations
,
December 1997 in “The British Journal of Psychiatry” This document outlines the indications, dosing, side effects, and contraindications for Epilim in epilepsy treatment, with no new research findings presented.
July 2026 in “Scientific Reports” This study found that, among women with type 1 diabetes, those with polycystic ovary syndrome did not show worse lipoprotein and inflammatory glycoprotein profiles compared to those without the syndrome, although they had more harmful HDL particle subclasses than women with typical PCOS.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.
May 2026 in “Comprehensive Psychoneuroendocrinology” This study evaluated factors influencing hair steroid concentrations in early infancy, finding small effects from birth mode, season, and age-related changes, suggesting hair analysis as promising for assessing long-term endocrine activity.