research Inactivation of Autophagy Leads to Changes in Sebaceous Gland Morphology and Function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
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research The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses
Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research 1H NMR-Based Lipidomics of Rodent Fur: Species-Specific Lipid Profiles and SCD1 Inhibitor-Related Dermal Toxicity
SCD1 inhibitors can cause skin issues in rodents.
research The Effect of Drugs on Hair
Drugs can change hair growth and this is important because it can upset people.
research Advances in Topical Therapy of Skin Diseases
New treatments for skin diseases in 1979 showed promising results with fewer side effects.
research Targeted Hair Follicle Delivery of Hydrophilic Molecules
Researchers developed a new method to deliver molecules to hair follicles to manage hair growth without damaging surrounding skin.
research Main Plenary Sessions: Summaries of Papers
The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.
research Synthesis and Study of Some 17a-Aza-D-Homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Proposing Vascepa (Icosapent Ethyl) as Supplemental Treatment for Persistent Post-Viral Symptoms of COVID-19: A Case Series
Icosapent ethyl may help treat long-lasting symptoms after COVID-19.
research Hyaluronate and Gelatin-Based Hydrogels Encapsulating Doxycycline as a Wound Dressing for Burn Injury Therapy
New hydrogel dressing with antibiotic speeds up burn healing and skin regeneration.
research Steroid Sulfatase Inhibitors: Role and Therapeutic Potential
Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.
research DGAT1 Modulates Hair Cycling and Is Essential for Retinoid Homeostasis in the Skin
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.
research Acne and Sebaceous Gland Function
Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.
research Acquired Pili Torti: A Structural Hair Shaft Defect in Anorexia Nervosa
Anorexia nervosa may cause a hair defect called pili torti due to malnutrition and high vitamin A levels.
research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates
Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
research Phytochemical Analysis of Eclipta Prostrata L. Leaves
Eclipta prostrata leaves contain various compounds with medicinal properties.
research ToF-SIMS Characterization of the Lipid Layer on the Hair Surface: The Damage Caused by Chemical Treatments and UV Radiation
Chemical treatments and UV radiation severely damage the lipid layer on hair.
research Emerging Drugs for Hypogonadism
New treatments for male hypogonadism are easier to use and target specific tissues to reduce side effects.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Current Treatment of Alopecia Areata
There are no FDA-approved treatments for Alopecia Areata, and current options have varying success and relapse rates.
research Use of Contact Immunotherapy in the Treatment of Skin Diseases Other than Alopecia Areata
Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
research Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia
Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.
research Ritlecitinib And Brepocitinib Demonstrate Significant Improvement In Scalp Alopecia Areata Biomarkers
Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.
research Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals
Different parts of the body have unique immune characteristics in their skin.
research Scalp Biomarkers During Dupilumab Treatment Support Th2 Pathway Pathogenicity in Alopecia Areata
Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.