33 citations
,
August 2018 in “Cochrane Database of Systematic Reviews” This review evaluates the efficacy and safety of enteral nutrition for maintaining remission in quiescent Crohn's disease but finds the evidence inconclusive and calls for further research.
6 citations
,
December 2024 in “F1000Research” In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.
258 citations
,
July 2005 in “Journal of lipid research” This study found that DGAT1 exhibits additional acyltransferase activities in vitro, including MGAT, wax synthase, and ARAT activities, suggesting these could be relevant to its in vivo functions.
91 citations
,
November 2008 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that DGAT1 functions as a key enzyme in murine skin to regulate retinoic acid levels and prevent retinoid toxicity, impacting hair cycle and sensitivity to retinol.
87 citations
,
April 1973 in “Endocrinology” This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.
22 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
14 citations
,
June 2011 in “Steroids” This study found that several dehydroepiandrosterone ester derivatives effectively reduced prostate and seminal vesicle weight in gonadectomized hamsters treated with testosterone, demonstrating potential antiandrogen effects comparable to Finasteride.
13 citations
,
January 2005 in “Chemical and Pharmaceutical Bulletin” This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.
6 citations
,
April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.
3 citations
,
September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
2 citations
,
December 2018 in “Natural Product Research” This study identified a new compound from fermented Carica papaya L. with moderate antioxidant and potent hair growth-stimulating activities in vitro.
August 2013 in “Fertility and Sterility” This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.
June 2006 in “Annales de Dermatologie et de Vénéréologie” This review highlights the potential benefits of spironolactone in dermatology, particularly for female acne, supporting its safety over long-term use without extensive testing, but presents no new clinical results.
5 citations
,
February 2025 in “Scientia Horticulturae” This study found that tomato plants inoculated with Enterobacter sp. SA187 grew better under salinity and heat stress, showing improved biomass, ion balance, chlorophyll content, and antioxidant enzyme activity, potentially enhancing crop tolerance to environmental stress.
May 2025 in “The Journal of Rheumatology” This case report from BIRDEM General Hospital describes a 17-year-old girl with systemic lupus erythematosus who developed a rare form of lupus enteritis affecting her colon and rectum. Her symptoms improved significantly after treatment with corticosteroids and immunosuppressants.
March 2024 in “European Journal of Neuroscience” This study, using a reporter mouse line, characterized diverse subtypes of dopaminergic neurons in the enteric nervous system, identifying unique subtypes with potential roles in gut function and disease.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers used a reporter mouse model to identify and characterize distinct subtypes of dopaminergic neurons in the gut's enteric nervous system, revealing novel populations with potential implications for understanding their roles and vulnerabilities in disease.
12 citations
,
May 2016 in “British Journal of Dermatology” This report describes a rare case of epidermolysis bullosa acquisita in a child developing during therapy with squaric acid dibutyl ester for alopecia areata, suggesting a possible link between the medication and disease onset.
10 citations
,
January 2014 in “Journal of Pharmaceutical Sciences” This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.
9 citations
,
April 2019 in “International Journal of Molecular Sciences” This research indicates that KCED-1 and KCED-2 effectively induce adiponectin production in human subcutaneous fat, which may promote hair growth on the scalp.
5 citations
,
February 2014 in “Journal of chemical ecology” This study determined the broad class and molecular species of glycerophospholipids in Eastern red bat sebum, highlighting differences from previous bat lung surfactant studies.
4 citations
,
May 2018 in “European journal of dermatology/EJD. European journal of dermatology” Fumaric acid esters might help treat alopecia areata, but more research is needed.
4 citations
,
January 2011 This thesis explores the synthesis and antiproliferative properties of phenylpropanoid sucrose esters, noting the absence of synthetic methods for most of this compound class due to their structural complexity.
2 citations
,
November 2009 in “DSpace (Federal University of Santa Catarina)” Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
January 2026 in “Food Science and Human Wellness” This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.
July 2018 in “European Medical Journal” This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
September 2015 in “Photodiagnosis and Photodynamic Therapy”
October 2021 in “VITEK Bidang Kedokteran Hewan” This case study reports on a 1-year-old male goat with various health issues including bloody stool, hair loss, and lice, treated with medication and supplements.