TLDR Fumaric acid esters might help treat alopecia areata, but more research is needed.
The retrospective analysis examined the use of fumaric acid esters in 13 patients with alopecia areata (AA), an autoimmune disease causing non-scarring hair loss. The study aimed to evaluate the effectiveness of this treatment, given the limited success of existing local and systemic therapies. The findings suggested that fumaric acid esters might offer a potential treatment option for AA, although the small sample size of 13 patients indicated that further research with larger cohorts would be necessary to confirm these results.
238 citations,
November 2016 in “Journal of The American Academy of Dermatology” Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.
56 citations,
October 2016 in “Journal of dermatological science” New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
14 citations,
January 2016 in “Annals of dermatology/Annals of Dermatology” Oral cyclosporine is more effective and safer than betamethasone for treating alopecia areata.
18 citations,
January 2015 in “International Journal of Trichology” Intralesional steroids are more effective for hair regrowth in alopecia areata than NBUVB, but combining them doesn't improve results.
44 citations,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
April 2019 in “International journal of research in dermatology” A child with rough nails also had hair loss and allergies.
