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270-300 / 1000+ resultsresearch The Health-Promoting Properties of Seaweeds: Clinical Evidence based on Wakame and Kombu
This review highlights the bioactive compounds in the brown seaweeds Undaria pinnatifida (wakame) and Saccharina japonica (kombu), detailing their various health benefits based on clinical studies, notably from Japan and elsewhere.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
In this study, the authors propose that drugs like trazodone and antipsychotics such as chlorpromazine, which can induce priapism, may help restore libido synaptic circuits, offering potential treatment for post-finasteride syndrome and post-SSRI sexual dysfunction.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.
research BUZZ: an essential gene for postinitiation root hair growth and a mediator of root architecture in Brachypodium distachyon
This research identified a genetic mutation in Brachypodium distachyon that initially allows root hair initiation but fails to elongate them, while also affecting root growth and nitrate sensitivity; the mutation is linked to a previously uncharacterized cyclin-dependent kinase-like gene.
research Alpinia zerumbet: A Review of the Chemistry, Quantity, and Pharmacological Properties of Selected Kavalactones
This review highlights the diverse potential medicinal properties of kavalactones from Alpinia zerumbet, which include antioxidant, anti-cancer, and anti-inflammatory activities, among others, and suggests fields for further research.
research Safer 1064 nm long-pulse frequency settings and safety eyewear setup to improve visualization of superficial veins
This letter discusses findings from an article by Sun et al. showing that neodymium doped yttrium aluminum garnet laser effectively treats prominent facial vasculature in patients with frontal fibrosing alopecia, but highlights concerns about the risk of iatrogenic scarring and suggests caution with treatment frequency.
research Inferring Spatially Resolved Transcriptomics Data from Whole Slide Images for the Assessment of Colorectal Tumor Metastasis: A Feasibility Study
In this study, deep learning models accurately predicted gene expression in whole slide images of colorectal cancer, with convolutional neural networks outperforming transformer and graph-based approaches in spatial RNA pattern prediction.
research 613 Bacteria induce skin regeneration via IL-1β signaling
This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.
research S2594 Autoimmune Hepatitis Due to Para-Aminobenzoic Acid
This case study reports a previously undescribed cause of drug-induced autoimmune hepatitis triggered by para-aminobenzoic acid (PABA), emphasizing the need for caution with this supplement.
research Neutrophil extracellular traps impair regeneration
This study found that although mature neutrophils and NETs are stimulated by a pro-regenerative cue, their presence actually hinders wound-induced hair follicle regeneration.
research 795 Bacteria induce skin regeneration
This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.
research Bacteria Induce Skin Regeneration Via Il-1β Signaling
This study found that skin bacteria contribute to regeneration in wound healing and WIHN by promoting IL-1β signaling, challenging the view that sterility is always beneficial for healing small wounds.
research Author response: Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.
research Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors
This study reports that a novel series of compounds can potently and selectively inhibit glycogen synthase kinase-3, which activates glycogen synthase in insulin receptor-expressing cells and primary rat hepatocytes.
research 176 The Prospective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study identifies clinical prognostic markers and establishes the foundation for large-scale translational research in cutaneous lymphoma
This study reported that in mycosis fungoides and Sezary syndrome, there is male predominance and younger age of presentation in early-stage disease, with significant data collection efforts supporting biomarker identification.
research 606 The role of diet in patients with autoimmune blistering disease: A survey of the International Pemphigus and Pemphigoid Foundation
This study observed that people with autoimmune blistering skin disorders report higher food intolerance rates, particularly avoiding alcohol, citrus, and spicy foods, and suggests potential dietary influences on symptom management.
research Liposomal Bupivacaine
No specific research results are reported in this abstract; it describes the scope and content of the Dermatologic Surgery journal, highlighting its comprehensive coverage of various dermatologic surgical procedures and its utility for professionals in this medical field.
research 1312 Nrf2 activation enhances the healing of cutaneous wounds through the activation of hair follicle stem cells
This study found that activation of the transcription factor Nrf2 in keratinocytes promotes wound healing in mice by expanding hair follicle stem cells, independent of changes in keratinocyte proliferation or migration.
research The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm
This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.
research Women Also Use 5α-Reductase Inhibitors—Reply
Women also use 5α-reductase inhibitors, and their effects differ from men.
research A Rare Case of Cronkhite-Canada Syndrome
This case report details a 71-year-old man diagnosed with Cronkhite-Canada Syndrome, highlighting the importance of early diagnosis and endoscopic evaluation due to the disease's progressive nature and significant mortality risk.
research 668 Activation of Nrf2 promotes wound healing by expansion of hair follicle stem cell populations
Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
research 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis
LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
research The usefulness of dermoscopy in canine pattern alopecia: a descriptive study
This study suggests that dermoscopy provides additional insights for diagnosing pattern alopecia in short coated dogs, beyond what is visible through standard dermatological examination.
research Effects of Castration on BPH
This commentary discusses the historical understanding of castration's effects on benign prostatic hyperplasia and reports no new clinical findings.
research 551 Nrf2 activation enhances cutaneous wound healing by expansion of hair follicle stem cell populations
Activating Nrf2 can improve wound healing by increasing hair follicle stem cells.
research Current Status of Fractional Laser Resurfacing
This overview highlights the effectiveness of fractional lasers, particularly fractional erbium:YAG, in treating various skin conditions with customizable settings and a short recovery time, while noting potential risks and the importance of tailored applications for different skin types.
research Reply
This letter clarifies a previous article's incorrect usage of terms prefabrication and prelamination, discussing how small, separate oral mucosa grafts can effectively reduce surgical morbidity in flap procedures.
research Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.
A mutation in the KRT74 gene causes woolly hair by affecting hair texture.