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This article reviews the current understanding of the localization, characteristics, and potential markers of epidermal stem cells, and reports no new experimental results.

This article reviews the role of epidermal proteins and regulatory mechanisms in skin diseases, emphasizing recent insights but reports no new experimental results.

This review discusses advances in understanding epidermal biology and pathology over the past two decades and highlights the significant progress yet acknowledges that much remains to be discovered; no new clinical results are reported.

This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.

This study found that transplanted ES cell-derived epidermal stem cells promoted the formation of epidermis, sweat gland-like, sebaceous gland-like, and hair follicle-like structures in mouse skin defects.

This essay discusses the establishment, maintenance, and role of skin stem cells in tissue homeostasis, wound repair, and their relation to skin cancer, without reporting new experimental findings.

This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.

This study observed that the expression of certain keratins during human epidermal development marks the tissue's commitment to stratification and keratinization processes.

This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.

In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.

This study found that the SVpgC2a keratinocyte cell line, used as a model for dysplastic epithelium, showed increased apoptosis, proliferation, and aberrant keratin expression compared to normal keratinocytes from buccal mucosa.

In this study, the staining properties of two types of cysts, epidermal and pilar, were found to differ, supporting their origins from the epidermis and the trichilemmal hair follicle layer, respectively.

This review examines the process of cornification as a mode of programmed cell death and outlines how keratinocytes activate anti-cell death mechanisms to maintain epidermal homeostasis, but reports no new results.

This review explores the role of Eph receptors and ephrins in skin cell processes, discussing their potential for therapeutic targeting in dermatological disorders, but it presents no new research findings.

This study demonstrated that hiPSC-derived hair-bearing skin organoids lacked sufficient type VII collagen at the epidermal-dermal junction, indicating a need for further maturation to model certain forms of epidermolysis bullosa effectively.

This study reviews the structural and functional aspects of cell-cell and cell-matrix junctions in sebocytes, emphasizing their roles in sebocyte differentiation and sebum secretion, and how these processes may change in pathological conditions, potentially providing insights for new skin disease therapies.

Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.

This study describes the structure and composition of the epidermal horny layer in elephant seals, noting that its keratinized cells are attached without a specialized fission zone, differing from the sloughing mechanism in reptiles.

Keratinocytes might turn into stem cells, but more research is needed to confirm this.

In this study using rat models, researchers found that subcutaneously implanted non-de-epithelialized flaps maintained persistent epidermal components, leading to potential complications, whereas de-epithelialized flaps showed gradual regression of remaining skin elements, lowering complication risks over time.

This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.

This study found that ablating centrosomes in developing epidermis alters keratinocyte division without majorly affecting differentiation, suggesting early epidermal development is driven by high proliferation and cell delamination.

This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.

This study reported that human induced pluripotent stem cell-derived skin organoids, used to model epidermolysis bullosa, have an epidermal-dermal junction largely lacking type VII collagen, which is important for skin structure.

This commentary discusses the role of the epidermis in hair follicle induction and reports no new research findings.

This review discusses the interactions between immune cells and the skin epithelium and their impact on maintaining barrier function, emphasizing the potential to enhance epithelial barrier function in inflammatory diseases.