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Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Different types of skin cells play specific roles in development, healing, and cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

The document concludes that while "hair follicle cloning" shows promise for unlimited donor hair, it faces challenges with consistency and safety in humans.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Red deer antler extract helps hair grow by extending the growth phase and increasing cell growth in hair follicles.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

TGF-β2 plays a key role in human hair growth and development.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Hair follicle cells can help heal wounds and study skin diseases.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.