research Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin
Mice skin has components that could help with hair growth and might be used for diabetes treatment.
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research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
research Interpretation Of The Yak Skin Single-Cell Transcriptome Landscape
The study mapped yak skin cells to understand hair growth better.
research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing
Fibroblast state switching is crucial for skin healing and development.
research Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation
Msx2 and Foxn1 are both crucial for hair growth and health.
research Sp6 Downregulation of Follistatin Gene Expression in Ameloblasts
Sp6 promotes tooth development by reducing follistatin levels.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research Tissue Homeostasis and Regeneration: Human Limitations and Potential
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
research Epidermal Stem Cells: An Update on Their Potential in Regenerative Medicine
Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Ox40-Cre-Mediated Deletion of BRD4 Reveals an Unexpected Phenotype of Hair Follicle Stem Cells in Alopecia
Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research Stem Cell Identification: In Vivo Lineage Analysis Versus In Vitro Isolation And Clonal Expansion
In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
research From Neural Crest Cells to Melanocytes: Cellular Plasticity During Development and Beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Epidermal Stem Cell Lineages: Roles in Skin Integrity, Stress Response, and Disease
Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells
Skin cancer often starts from Lgr5+ progenitor cells.
research Fibroblasts and Wound Healing: An Update
Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
research Skin Shedding and Tissue Regeneration in African Spiny Mice (Acomys)
African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Microenvironmental Reprogramming of Thymic Epithelial Cells to Skin Multipotent Stem Cells
Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research Clonal Analysis of Stem Cells in Differentiation and Disease
New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.