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Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.

K16 can partially replace K14 but causes hair loss and skin issues.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.

Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Skin grafting can help repigment vitiligo, but it's less effective for widespread cases due to the Koebner phenomenon.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

The PP2A-B55α protein is essential for brain and skin development in embryos.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Patients with autoimmune blistering diseases experience a reduced quality of life, with the need for better measurement tools, especially for those with mucous membrane pemphigoid.

New treatments for skin and hair repair show promise, but further improvements are needed.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Laminin 332 is essential for normal skin cell behavior and structure.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.

Notch signalling helps skin cells differentiate and prevents tumors.

The new matrix improves skin regeneration and graft performance.

Choosing the right method to separate skin layers is key for good skin cell research.

Most patients with autoimmune blistering diseases experienced some hair loss, which may be underreported and linked to disease severity.