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research Androgen excess: Investigations and management
This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.
research Treatment of Polycystic Ovarian Syndrome using Electroacupuncture: A Case Report
This report discusses electroacupuncture as a complementary treatment for PCOS and suggests it may improve symptoms by enhancing ovulation and reducing testosterone and LH levels, but does not present new clinical results.
research Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats
In this study, epithelial cell-derived exosomes promoted fibroblast migration and inhibited their proliferation, suggesting a role in dermal condensate formation and hair follicle morphogenesis in cashmere goats.
research Post-finasteride syndrome: survey of dermatologists from the Spanish Hair and Nail Disorders Group
In this study, dermatologists from the Spanish Hair and Nail Disorders Group viewed post-finasteride syndrome as rare and primarily of psychiatric origin, with limited scientific evidence supporting its existence.
research The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study
This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.
research Novel micelle formulations to increase cutaneous bioavailability of azole antifungals
This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.
research Epigenetic Effects of Finasteride on Human Leydig Cells
This study identified specific genes and pathways in human Leydig cells that may contribute to Post-finasteride Syndrome, potentially informing future treatments to reverse persistent side effects.
research Extrapulmonary disorders associated with Rhodococcus equi infection in foals: 150 cases (1987–2007)
Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.
research Protein-Losing Enteropathy as the First Presentation of Systemic Lupus Erythematosus in a Resource-Limited Setting in Sri Lanka: A Case Report
This case report details a 38-year-old woman in Sri Lanka diagnosed with systemic lupus erythematosus-associated protein-losing enteropathy, identified through hypoalbuminemia and EULAR criteria in a resource-limited setting.
research M2 Macrophage and Extracellular Matrix Genes Are Enriched in High‐Activity Lichen Planopilaris
In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.
research Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages
This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.
research Therapeutic options for erosive pustular dermatosis of the scalp: a systematic review*
This study suggests that topical corticosteroids, potentially combined with oral zinc and followed by topical calcineurin inhibitors, may be effective for managing erosive pustular dermatosis of the scalp.
research Non-Edg family LPA receptors: the cutting edge of LPA research
This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.
research Effectiveness of Fenugreek Seeds against Polycystic Ovarian Syndrome
This study reports that fenugreek seed extract (Furocyst®) improved body weight, ovarian cysts, ovary size, hair growth, and menstrual regularity in women with PCOS, indicating its potential as an effective phytotherapeutic option for managing the condition.
research Time Perspective as a Mediator of Depressive Symptoms in Patients with Polycystic Ovary Syndrome
This discussion highlights the importance of psychoeducation and communication for patients in risk groups to foster hope and manage their life situations; it presents no new empirical findings.
research Phytochemical Analysis of Eclipta prostrata L. (L.) Leaves
This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
research Follicular Unit Extraction
This article outlines the technical aspects, benefits, and challenges of follicular unit extraction for hair transplantation, but it reports no new clinical findings.
research Comment on “The post-finasteride syndrome: possible etiological mechanisms and symptoms”
Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
research Finasteride
research Frontal fibrosing alopecia and lichen planus pigmentosus: diagnosis and therapeutic challenge
This case study discusses a postmenopausal woman's frontal fibrosing alopecia and lichen planus pigmentosus, controlled with corticosteroids and finasteride, highlighting diagnostic and therapeutic challenges in scarring alopecia.
research Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses
This review discusses the role of fibroblast heterogeneity in determining skin scarring versus regeneration and reports no new results, highlighting opportunities for developing antiscarring therapies.
research Minimizing Skin Scarring through Biomaterial Design
This review examines the major biomaterials used in skin wound healing and evaluates experimental therapies but reports no new research findings.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
This review discusses the formation and maintenance of hair follicles through dynamic cellular changes and signaling pathways, presenting a comprehensive overview but providing no new experimental findings.
research Regulatory T cells in skin regeneration and wound healing
This review explores the crucial role of regulatory T cells in skin wound healing, emphasizing their involvement in balancing immune responses and promoting regeneration. It also discusses Tregs' operations in fibrosis, keloidosis, and scarring, suggesting a potential avenue for novel treatments.
research Exploring the Role of Dermal Sheath Cells in Wound Healing and Fibrosis
This review explores the roles of dermal sheath cells in wound healing, highlighting their multifunctional contributions to inflammation, proliferation, and extracellular matrix remodeling, and proposes new insights into tissue regeneration and repair, especially in differentiating between hairy and non-hairy skin sites.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.
research Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles
This study found that a microneedle patch integrating curcumin-loaded vesicles and a stem cell-derived matrix showed promise in reducing hypertrophic scars and promoting hair follicle formation in a rabbit model.
research States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility
The researchers in this study found that neonatal mouse skin fibroblasts show distinct chromatin landscapes directing differentiation into dermal papilla or adipocyte lineages, and such plasticity may inform strategies for enhancing regenerative capacities in adult skin.
research Pathogenesis of Hand-Foot Syndrome induced by PEG-modified liposomal Doxorubicin
In this study using an animal model, researchers found that PEGL-DOX, unlike DOX, causes Hand-Foot Syndrome due to reactive oxygen species interacting with skin tissue, leading to skin-specific inflammatory responses.