Post-Finasteride Syndrome: Survey of Dermatologists from the Spanish Hair and Nail Disorders Group

    March 2026 in “ Actas Dermo-Sifiliográficas ”
    O.M. Moreno-Arrones, D. Saceda-Corralo, JL. Gómez-Cano, A. Gómez-Zubiaur, JM. Mir-Bonafé, C. Serrano-Falcón, G. Garnacho-Saucedo, R. Grimalt, A. Combalia, E. Fernández, S. Vañó-Galván
    TLDR Most dermatologists think post-finasteride syndrome is rare, possibly psychiatric, and needs more research.
    This study surveyed 54 dermatologists from the Spanish Hair and Nail Disorders Group to assess their perception of post-finasteride syndrome (PFS). The results showed that 83.3% of respondents had never encountered PFS in their practice, and 98.1% believed it has a psychiatric origin. Most dermatologists thought adverse effects of 5-alpha-reductase inhibitors are reversible after discontinuation. While sexual dysfunction was possibly linked to 5-ARIs, cognitive impairment, anxiety, and depression were largely considered unrelated. Consensus was reached on 13 of 15 items, with 90.7% agreeing that scientific evidence on PFS is poor and 85.1% identifying young men with pre-existing anxiety or depression as a specific patient profile. The conclusion highlights the need for high-quality studies to guide diagnosis and management of PFS.
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