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Preclinical Evidence and Underlying Mechanisms of Polygonum Multiflorum and Its Chemical Constituents Against Cognitive Impairments and Alzheimer’s Disease

research Preclinical Evidence and Underlying Mechanisms of Polygonum multiflorum and Its Chemical Constituents Against Cognitive Impairments and Alzheimer’s Disease

4 citations , June 2024 in “Journal of pharmacopuncture”

This review compiles current experimental research on Alzheimer's and cognitive impairment models, highlighting the potential of *Polygonum multiflorum* for treating neurological disorders and suggesting a foundation for future clinical trials.

research P.1.g.018 Cognitive performance in adolescents with anorexia nervosa: subgroups in relation to neuropsychological impairment

August 2008 in “European Neuropsychopharmacology”

This study identified significant correlations between self-esteem, psychiatric symptoms, and health-related quality of life in peritoneal dialysis patients.

research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride

81 citations , June 2014 in “American Journal of Men's Health”

This study highlights that adverse effects from finasteride may persist in men after discontinuation, indicating a potential "post-finasteride syndrome.

research Abstract 4993: A longitudinal examination of nutritional-inflammatory biomarker associations with cancer related cognition, treatment side effects and quality of life in newly diagnosed older adults undergoing chemotherapy

April 2025 in “Cancer Research”

This study examined older adults undergoing chemotherapy and found that nutritional-inflammatory biomarker ratios were significantly linked to cognitive impairments, treatment side effects, and quality of life indicators, suggesting these lab measurements might help identify high-risk individuals for intervention.

research PSYCHOLOGICAL-PSYCHIATRIC CONSEQUENCES OF ALOPECIA: A STUDY OF PATIENTS’ COGNITIVE FUNCTIONING

December 2024 in “Ukrains kyi Visnyk Psykhonevrolohii”

This study found that women with mixed alopecia experienced significant cognitive impairments, particularly those with adaptation disorders, with symptoms like rapid fatigue and impaired concentration being most prevalent. The cognitive patterns are complex and require further investigation to inform tailored rehabilitation strategies.

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community Experiencing cognitive effects while on Dutasteride

5 upvotes 6 days ago

The user experienced fatigue, brain fog, and dizziness after taking Dutasteride for hair loss, suspecting it might be a side effect. They plan to consult a doctor and get blood work done, while others in the conversation discuss potential cognitive effects and compare Dutasteride to Finasteride.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community People who suffered from fin sides, what treatment are you doing now?

4 upvotes 5 years ago

The conversation discusses transitioning from oral finasteride due to side effects to using topical finasteride with stemoxydine, with some users reporting fewer side effects. Other treatments mentioned include minoxidil, microneedling, nizoral shampoo, and LLLT caps.

community 2.5 years on topical finasteride (0.1% fin + 7% min): hair success and why I stopped

in Finasteride/Dutasteride 20 upvotes 7 months ago

Topical finasteride with minoxidil effectively stabilized and thickened hair but caused side effects like brain fog, reduced libido, and emotional flattening, leading to discontinuation. The user switched to a new regimen including minoxidil, KX-826, and other treatments, noting improvements in libido and vivid dreams after stopping finasteride.

community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 10 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

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