Post-Finasteride Syndrome: Our Current Knowledge

    July 2020 in “ Vestnik urologii
    А А Галушкин, Д. Г. Лихих, М. И. Коган
    TLDR The cause of post-finasteride syndrome is unclear and needs more research.
    The document discussed post-finasteride syndrome (PFS), a condition that was reported to occur in some individuals after the use of finasteride, a medication commonly used to treat hair loss and benign prostatic hyperplasia. PFS was characterized by persistent sexual, neurological, and physical side effects that continued even after discontinuation of the drug. The article reviewed the current understanding of PFS, highlighting the need for further research to better understand its mechanisms and to develop effective treatment strategies. It emphasized that while the syndrome was recognized, the exact prevalence and pathophysiology remained unclear, necessitating more comprehensive studies to validate and explore these aspects.
    Discuss this study in the Community →

    Research cited in this study

    14 / 14 results

    Related Community Posts Join

    6 / 1000+ results

      community Age 18 vs Age 25, the importance of starting early

      in Progress Pictures  867 upvotes 2 weeks ago
      An 18-year-old began using Finasteride and Topical Minoxidil for hair loss, later switching to Oral Minoxidil and Dutasteride by age 25. The conversation emphasizes early treatment, potential side effects, and differing opinions on medication effectiveness.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 9 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  73 upvotes 4 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 1 month ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

    Related Research

    1 / 1 results