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This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.

In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.

This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.

Testosterone may both worsen and protect against COVID-19 effects in men.

This article reviews recent data suggesting that metformin may be beneficial for anovulatory PCOS patients with normal BMI and clomiphene resistance but emphasizes that more studies are needed to confirm these findings.

This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.

This article discusses laboratory and physical markers that may help detect androgenic anabolic steroid abuse in athletes and reports no new primary research results.

This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.

In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.

This study found that certain non-dermatophytic moulds, specifically *Absidia* sp., *Cladosporium tenuissimum*, and *Aspergillus welwitschiae*, can cause skin symptoms such as discoloration and lesions in albino mice, suggesting potential virulence due to enzyme activity.

In this case report, a 45-year-old man with treatment-resistant androgenetic alopecia experienced hair regrowth during oral bicalutamide treatment but also suffered adverse effects leading to discontinuation, highlighting the need for further studies on the safety and role of androgen receptor blockade in hair loss.

This study found that adding a SULT1A1 enzyme booster to minoxidil treatment improved hair growth response in 65% of androgenetic alopecia patients who were previous non-responders to minoxidil alone, with females benefiting more than males.

This study reported that mannan oligosaccharides improved the fur quality, immune response, antioxidant status, and gut microbiota of fur-growing raccoon dogs, suggesting they could potentially replace antibiotics in their diet.

This in vitro study found sex chromosome differences affect steroidogenic enzyme activity and androgen receptor expression in human skeletal muscle cells, showing varied responses to testosterone exposure between 46XY and 46XX cells.

This study on diabetic rats reported that Ziziphus spina-christi ethanol leaf extract significantly reduced blood glucose levels and improved liver and kidney function, suggesting possible benefits in managing diabetes symptoms in this animal model.

This case report details a patient with autoimmune hypothyroidism who experienced multiple health issues that improved with comprehensive treatment including Thyroxin replacement and other supportive measures.

This study observed that Egyptian patients with discoid lupus erythematosus have significantly lower serum vitamin D3 and antioxidant levels compared to healthy controls, suggesting potential benefits of vitamin D3 and antioxidant supplementation.

This article reviews the efficacy of Finasteride for treating female androgenic alopecia, highlighting increased hair counts and density but reports no new clinical results.

This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.

This case report highlights a 53-year-old woman who developed acute hepatitis after taking shou-wu-pian for eight months, suggesting that Chinese herbal preparations can sometimes cause liver damage.

Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.

This study found that PCOS women with COVID-19 had lower ACE2 levels and higher insulin resistance, suggesting increased cardiovascular risk.

This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.

This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.

This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.

This study explored a new dutasteride nanocarrier for alopecia therapy, concluding that ingredient concentration is key to achieving the optimal particle size, stability, and skin permeation for extended drug release.

In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.

This review discusses the biochemical and psychological impacts of polycystic ovary syndrome on immune functions against COVID-19 but reports no new clinical results.

This review observes higher ACE2 expression in myocardial and lung tissues of heart failure and COPD patients but finds no link between RAAS inhibitors and COVID-19 severity.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.