5α-Reductase, An Enzyme Regulating Glucocorticoid Action In The Testis Of Rhinella Arenarum (Amphibia: Anura)

January 2012 in “ General and Comparative Endocrinology ”

Amelia J. Tesone, Eleonora Regueira, Luis Fabián Canosa, Nora R. Ceballos

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research 5α-Reduced Glucocorticoids: A Story of Natural Selection

46 citations , September 2011 in “Journal of Endocrinology”

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

research An Overview on 5α-Reductase Inhibitors

219 citations , October 2009 in “Steroids”

5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.

research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.