Unexpected Hair Regrowth Following Oral Bicalutamide Exposure in a Male Patient With Androgenetic Alopecia and a Suboptimal Response to Conventional Therapies: A Case Report

    July 2026 in “ Cureus ”
    Jared Martínez Coronado, Kenia Dominguez Romo, Luisa F Vazquez Enriquez … Carolina Pico
    Studysummary In this case report, a 45-year-old man with treatment-resistant androgenetic alopecia experienced hair regrowth during oral bicalutamide treatment but also suffered adverse effects leading to discontinuation, highlighting the need for further studies on the safety and role of androgen receptor blockade in hair loss.
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    Research cited in this study 5

    1. Bicalutamide in Dermatology: A Narrative Review Indian Dermatology Online Journal · 2024
    2. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    3. Androgenetic Alopecia: Therapy Update Drugs · 2023
    4. Bicalutamide and the New Perspectives for Female Pattern Hair Loss Treatment: What Dermatologists Should Know Journal of Cosmetic Dermatology · 2022
    5. Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients Journal of The American Academy of Dermatology · 2020