Are there any men here who have taken bicalutamide without estradiol?
    7/20/2022

    From the encyclopedia
    Bicalutamide →

    a nonsteroidal anti-androgen, most commonly used orally for women

    Cyproterone →

    a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    At a glance
    In this general discussion post, the primary subjects mentioned are
    💊 Cyproterone Acetate (oral) 10mg once a week 3 months
    💊 Dutasteride (oral) daily
    💧 Minoxidil (topical) since June last year
    💧 RU58841 (topical) 40mg daily 8 months
    the tone is 😐 neutral with some growth results.

    Other terms

    Men discussing hair loss treatments, including bicalutamide, cyproterone acetate, dutasteride, minoxidil, and RU58841. They share experiences and concerns about side effects like infertility, liver health, and feminization.
    View this post in the Community →

    Similar Community Posts Join

    5 / 5 results

      community Sugar and hairloss

       10 upvotes 5 years ago
      Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.

      community Switch from fin to dut and its worse

       4 upvotes 1 year ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

      community Hair loss treatment iceberg: what does it look like?

      in Chat  146 upvotes 1 month ago
      Hair loss treatments range from common options like biotin, minoxidil, and finasteride to more obscure methods like RU58841 and experimental drugs. Hair transplants are widely known, while treatments like stool transplants and spironolactone are less common.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

       55 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

    Related Research

    6 / 6 results
      New Therapeutics in the Management of Androgenetic Alopecia

      research Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique

      March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”
      This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
      Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment

      August 2025 in “Drug Design Development and Therapy”
      This review article examines current drugs for androgenetic alopecia, focusing on their mechanisms and clinical efficacy, noting that while finasteride and minoxidil are commonly approved treatments, new drugs targeting different pathogenic pathways have emerged, offering a broader understanding and reference for AGA treatment options.
      Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

      research Drug discovery for alopecia: gone today, hair tomorrow

      70 citations , February 2015 in “Expert Opinion on Drug Discovery”
      This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.