research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
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research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Induction of Psoriasiform Changes in Guinea Pig Skin by Propranolol
Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
research Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angioedema
The conclusion suggests a new way to classify bradykinin-mediated angio-oedema based on different causes and its possible link with urticaria, which could improve diagnosis and treatment.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue
The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as a Promising Option
Adding licorice gel to laser treatment is more effective for reducing facial hair than laser alone.
research Structure-Guided Manipulation of the Regioselectivity of the Cyclosporine A Hydroxylase CYP-sb21 from Sebekia Benihana
Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.
research A Review of U.S. Patents in the Field of Organic Process Development Published During July and August 2004
The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
research Mechanisms of Impairment in Hair and Scalp Induced by Hair Dyeing and Perming and Potential Interventions
Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Index
The document is a detailed guide on skin conditions and treatments for dermatologists.
research Therapeutics of Premature Hair Graying: A Long Journey Ahead
Effective treatments for premature hair graying still require significant research.
research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome
Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
research Bioabsorbable Nano-Micelle Hybridized Hydrogel Scaffold Prevents Postoperative Melanoma Recurrence
A special gel with medicine helps prevent melanoma from coming back after surgery.
research Efficacy of Autologous Stromal Vascular Fraction Injection in the Treatment of Androgenic Alopecia
SVF injections improve hair growth and reduce hair loss in people with androgenic alopecia.
research Catalytic Antibodies in Normal and Systemic Lupus Erythematosus
Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
research Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications
Human hair keratin can be used in many medical applications.
research Atypical Formations of Gintonin Lysophosphatidic Acids as New Materials and Their Beneficial Effects on Degenerative Diseases
New ginseng compounds may help treat degenerative diseases.
research Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An In Vitro and In Vivo Study
Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets
Choosing the right method to separate skin layers is key for good skin cell research.
research Fullerene C60 with Cytoprotective and Cytotoxic Potential: Prospects as a Novel Treatment Agent in Dermatology
Fullerene C60 shows promise as a new treatment for various skin conditions.
research Cutaneous Gene Therapy
Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.
research Exploration of Nutraceutical Potential of Herbal Oil Formulated from Parasitic Plant
Herbal oils from Cuscuta reflexa help with hair growth, dandruff, and hair fall.
research Case Report: NUDT15 Polymorphism and Severe Azathioprine-Induced Myelosuppression in a Young Chinese Female with Systemic Lupus Erythematosus: A Case Analysis and Literature Review
Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.
research Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
Advanced techniques and technologies can improve burn wound healing, but more research is needed.
research Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Peptide-based hydrogels are promising for healing chronic wounds effectively.