May 2026 in “SKIN The Journal of Cutaneous Medicine” In this case report, a 60-year-old woman with alopecia areata and type 1 diabetes experienced hypoglycemic seizures after starting baricitinib, though reducing the dose alleviated these episodes; the study highlights the need for caution and glucose monitoring when using JAK inhibitors in at-risk patients.
4 citations
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January 2020 in “Journal of family medicine and primary care” This case report describes a 35-year-old male with Type 2 diabetes who experienced scalp hair loss after increasing his dose of Teneligliptin without supervision, which resolved after discontinuing the medication.
21 citations
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April 2011 in “Epilepsia” This open-label study suggests that combining valproate, lamotrigine, and a benzodiazepine can significantly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies.
5 citations
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February 2025 in “Frontiers in Immunology” This study highlights emerging research on lactate's biological roles in skin health, emphasizing its function as a signaling molecule that regulates skin barrier and immunity, and notes its therapeutic potential for skin conditions such as tumors and inflammatory diseases.
September 2022 in “Journal of The American Academy of Dermatology” In this study, the rate of hyperkalemia in women taking spironolactone for acne and related issues was low, but frequent monitoring of potassium trends during treatment may be advisable.
11 citations
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April 2018 in “Epilepsy research” This study indicated that administering letrozole to Swiss albino mice may have anticonvulsant effects against kainic acid-induced seizures by inhibiting testosterone aromatization to 17β-estradiol and increasing anticonvulsant metabolites in the hippocampus.
88 citations
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January 2001 in “Dermatology” This study found that the monophasic oral contraceptive ethinylestradiol/chlormadinone acetate was more effective in treating mild to moderate papulopustular acne in women than ethinylestradiol/levonorgestrel.
116 citations
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December 2013 in “European journal of endocrinology” This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.
1 citations
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June 2023 in “Cureus” In a retrospective study, researchers found that topical spironolactone improved tear film quality and reduced inflammation related to meibomian gland dysfunction and evaporative dry eye in patients, demonstrating good tolerability and suggesting it as a potential therapy for managing the condition.
32 citations
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January 2007 in “KARGER eBooks” This review discusses severe insulin resistance syndromes, highlighting their diagnostic challenges, potential novel therapies like leptin replacement, and suggests metformin and lifestyle changes in its absence; no new clinical results are reported.
24 citations
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July 1980 in “Journal of Toxicology and Environmental Health” This study found that feeding norethindrone acetate to albino rats over two years caused various dose-related health effects, such as growth retardation and liver changes, but did not increase overall tumor incidence.
January 2026 in “American Journal of Translational Research” In this study, the combination of metoprolol and spironolactone in patients with coronary heart disease and heart failure significantly improved cardiac function and reduced inflammation and oxidative stress markers compared to spironolactone alone, with better clinical efficacy and fewer adverse effects.
7 citations
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January 2025 in “Journal of Medicinal Chemistry” This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.
101 citations
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January 1985 in “British Journal of Dermatology” This article discusses oral spironolactone therapy for female patients with acne, hirsutism, or androgenic alopecia and reports no new clinical results.
July 2015 in “Reactions weekly” Lamotrigine can cause hair loss in some patients.
53 citations
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November 2006 in “Journal of Endocrinology” This study found that prolactin plays a direct role in regulating the timing of hair growth cycles in mice by affecting the skin, rather than through other endocrine factors.
February 2021 in “Facta Universitatis” This review discusses the current understanding of prolactin's role in female reproductive health and the diagnosis and treatment of hyperprolactinaemia but reports no new clinical findings.
May 2026 in “Pharmaceuticals” This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.
36 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” In this animal study, rats given high doses of ethynylestradiol showed dose-related estrogenic effects, delayed tumor onset in females, and no overall increase in tumor incidence compared to controls.
142 citations
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November 2009 in “BMC Complementary and Alternative Medicine” This study supports the traditional use of T. procumbens for diabetes treatment, showing improvements in body weight and glucose tolerance with no toxicity signs in normal rats.
1 citations
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July 2024 in “Journal of Assisted Reproduction and Genetics” 2 citations
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July 2018 in “Journal of pediatric epilepsy” This case report describes a 13-year-old girl with epilepsy who experienced hair loss within two months of starting levetiracetam, marking it as the first report of this side effect in this age group.
34 citations
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May 1987 in “European Journal of Pediatrics” This study concluded that Buserelin can effectively inhibit gonadal activity in children with central precocious puberty over 18 months, potentially improving final height predictions with prolonged treatment.
October 2015 in “Reactions Weekly” A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.
This trial will compare the effectiveness of spironolactone to doxycycline for treating acne in adult females, potentially offering an alternative to antibiotics and isotretinoin.
15 citations
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January 2024 in “Chemical Engineering Journal”
April 2017 in “Journal of Investigative Dermatology” This study suggests that sirolimus and propranolol may reduce abnormal lymphatic endothelial cell proliferation in lymphatic malformations, potentially improving vessel function and patient outcomes.
December 2021 in “Journal of pharmaceutical research international” This review discusses the potential and varied uses of spironolactone in dermatological conditions such as acne, hidradenitis suppurativa, hirsutism, and female pattern androgenetic alopecia, emphasizing dosage, treatment recommendations, and adverse effects for practical clinical use.
3 citations
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July 2025 in “Obesity Facts” This review examines how GLP-1 receptor agonists might impact metabolic and reproductive outcomes in polycystic ovary syndrome, but it reports no new clinical findings and highlights the need for further research.
6 citations
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May 2018 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study found that adjusting plant growth conditions, such as the use of elicitors like yeast extract and methyl jasmonate, increased wedelolactone production in Eclipta alba cell suspension culture.