TLDR A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.
A 61-year-old woman developed erosive pustular dermatosis of the scalp (EPDS) after using latanoprost, which she was taking for mild frontotemporal androgenetic alopecia. Following the application of a 0.1% ternary solution of latanoprost, she experienced eroded, pustular, and crusted lesions on her scalp. Physical and histologic examinations confirmed the diagnosis of EPDS, characterized by pustules, erosions, scales, and a loss of normal collagen architecture around hair follicles. Upon discontinuing latanoprost and starting treatment with methylprednisolone, zinc sulphate, and clobetasol propionate, her symptoms resolved after 6 weeks, although she had residual scarring alopecia. She remained symptom-free at the 30-week follow-up.
21 citations,
January 2015 in “Dermatologic Therapy” Latanoprost may cause scalp inflammation and delayed healing.
9 citations,
July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
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January 2015 in “Dermatologic Therapy” Latanoprost may cause scalp inflammation and delayed healing.
1 citations,
December 2022 in “Life” Topical corticosteroids are the main treatment for Erosive Pustular Dermatosis, but recurrence is common after stopping treatment.
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October 2013 in “Actas Dermo-Sifiliográficas” Customized medications made through compounding can be beneficial for various skin conditions but require careful regulation and collaboration between doctors and pharmacists.
53 citations,
February 2017 in “Journal of The American Academy of Dermatology” The conclusion is that high-potency steroids or tacrolimus are effective treatments for erosive pustular dermatosis of the scalp.
