10 citations
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July 2014 in “Veterinary dermatology” This study found that deslorelin may promote hair regrowth in intact male dogs with hair cycle arrest, but had no effect on neutered females.
April 2025 in “Frontiers in Pharmacology” This study found that targeting RARβ and RXRA with CANA, in combination with MPA, could help overcome progestin resistance by restoring BAX levels and downregulating CRABP2, suggesting a novel strategy for improving clinical efficacy in this context.
October 1986 in “Inpharma” Spironolactone helps reduce hair growth in women with hirsutism but may cause menstrual irregularities.
10 citations
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September 2015 in “Gynecological Endocrinology” In this study, spironolactone and spironolactone plus metformin both significantly reduced hirsutism scores in women with PCOS, but the combination therapy was not more effective than spironolactone alone regarding BMI, hormone levels, or insulin resistance.
3 citations
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October 2024 in “Advances in Therapy” In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.
December 2025 in “Fertility and Sterility” Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.
3 citations
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April 1977 in “PubMed” In this study, patients with varying severities of acne, seborrhoea, and hirsutism responded differently to Cyproteronacetate and Ethinyloestradiol treatment, with improvement rates dependent on symptom severity and treatment duration.
Low-dose spironolactone can be effective for treating hair loss in women.
17 citations
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October 2013 in “Der Hautarzt” 7 citations
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August 2025 in “European Journal of Endocrinology” The authors concluded that incorporating routine endocrinology consultations into transplant care could address CNI-related endocrine toxicities, but prospective studies are needed to assess the impact on graft and patient survival.
This study found that men with early-onset androgenic alopecia may be partially resistant to the cardiometabolic benefits of bromocriptine compared to those with normal hair growth.
44 citations
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June 1985 in “Fertility and sterility” This study suggests that combination drug therapy with spironolactone and either oral contraceptives or dexamethasone effectively manages unresponsive hirsutism, with eight of nine patients achieving satisfactory clinical responses.
October 2025 in “International Journal of Dermatology” This review suggests weak associations between GLP-1 receptor agonists and increased reports of hair loss, particularly with semaglutide and tirzepatide, while cases of hair regrowth were also occasionally documented.
14 citations
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April 2005 in “African Journal of Reproductive Health” This article reviews non-biodegradable progestational subdermal implants as long-acting contraceptives for women, discussing their effectiveness, associated side effects, and implementation challenges without reporting new clinical results.
7 citations
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January 2016 in “Case reports in pediatrics” This study reports that antiandrogen medication, specifically 50 mg/day of spironolactone, showed an adequate clinical response in treating breast hypoplasia associated with Becker's nevus syndrome.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” In this study, levothyroxine therapy showed no significant effect on blood sugar level changes in children with growth hormone deficiency in Saudi Arabia.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that nanostructured lipid carriers loaded with spironolactone might improve localized delivery to hair follicles for treating androgenic alopecia, potentially minimizing systemic side effects.
1 citations
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July 2021 in “Current nanomedicine” This study found that nanostructured lipid carriers could serve as a promising vehicle for topical Acitretin delivery in psoriasis treatment, potentially reducing oral side effects and enhancing patient compliance.
November 2024 in “Rheumatology Advances in Practice” In this case report, the use of ocrelizumab in the second trimester of a high-risk pregnancy with active juvenile-onset systemic lupus erythematosus resulted in a successful birth without complications, although its safety in pregnancy remains unlicensed and further evaluation is needed.
1 citations
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May 2023 in “Annales d'Endocrinologie” In this study, researchers found that metformin improved glycaemic control and other metabolic parameters in non-diabetic patients on glucocorticoid treatment, also reducing pneumonia risk and hospital admissions, suggesting a potential advantage for routine use in this population.
22 citations
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January 2013 in “Journal of The American Academy of Dermatology” This review discusses the role of contraceptives in dermatology, particularly for acne treatment and managing patients on teratogens, but reports no new clinical results.
10 citations
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May 2020 in “Journal of The American Academy of Dermatology” This study found that spironolactone was not independently associated with increased breast cancer recurrence and may be considered for treating alopecia in survivors.
16 citations
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March 2016 in “Clinical ophthalmology” In this study, bimatoprost 0.03% was effective and well-tolerated for improving eyelash hypotrichosis in healthy adolescents, but not for those with the condition due to chemotherapy or alopecia areata.
29 citations
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October 2009 in “Pharmacology Biochemistry and Behavior”
16 citations
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August 2014 in “International Journal of Women's Health” The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.
This study found that sodium valproate improved seizure control in children with epilepsy, with increased weight gain being the most common side effect reported.
March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders.
44 citations
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October 2016 in “Epilepsia” This study demonstrated that the glycolytic inhibitor 2-deoxy-D-glucose enhances antiseizure effects by potentiating extrasynaptic tonic GABAergic inhibition through neurosteroidogenesis in hippocampal slices.
July 2026 in “Journal of Investigative Dermatology” GLP-1 therapies can cause hair loss, but hair often regrows after stopping or reducing the drug.
37 citations
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November 2019 in “Journal of Microbiology and Biotechnology” This study found that loliolide enhanced hair growth-related functions in 3D dermal papilla spheroids by activating AKT/β-catenin signaling pathways, with increased expression of related growth factors and genes.