Medical Notes in Parliament: Retrospective Analysis of Epilepsy Treatment in Children

    July 1911 in “ BMJ ”
    TLDR Sodium valproate improved epilepsy control in most children but often caused weight gain and other mild side effects.
    A retrospective analysis of 100 children with epilepsy treated with sodium valproate showed improved fit control in 77 patients, particularly in those with generalized epilepsy. While severe side effects like acute liver disease and pancreatitis were not observed, milder side effects were common, affecting 65 patients. The most frequent side effect was increased weight gain, occurring in 44 cases, followed by transient gastrointestinal disturbances (20), lassitude (9), transient hair loss (6), transient enuresis (7), and aggressive behavior (4).
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 124 results

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  4 upvotes 1 year ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

    Similar Research

    5 / 1000+ results