8 citations,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
7 citations,
April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
1 citations,
May 2009 in “Wiley-Blackwell eBooks” Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
1 citations,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
June 2023 in “Journal of multidisciplinary sciences” PCOS may increase the risk of certain cancers.
March 2022 in “International journal of pharmaceutical sciences review and research” PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.
90 citations,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
August 2024 in “Medicine” Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
36 citations,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
19 citations,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
2 citations,
May 2023 in “Current Nutrition Reports” Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.
1 citations,
July 2023 in “Frontiers in Immunology” Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
January 2024 in “Biology of sex differences” Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
195 citations,
July 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
10 citations,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
April 2006 in “Current Opinion in Endocrinology & Diabetes” Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
March 2024 in “Advances in obstetrics and gynecology research” Combining hysteroscopy with Diane-35 improves outcomes and reduces recurrence of endometrial polyps.
February 2023 in “Frontiers in Pharmacology” Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
451 citations,
March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
22 citations,
July 2014 in “Hormones” Metformin may help treat neuroendocrine tumors.
1 citations,
May 2022 in “IntechOpen eBooks” Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
7 citations,
January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
2 citations,
December 2013 in “Cancer research” Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
January 2023 in “European journal of gynaecological oncology” KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.