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Stem cells in eccrine glands could be used for regenerative medicine.

Noggin promotes skin tumors by activating certain cell signaling pathways.

This study found that exosomes derived from hypoxia-conditioned mesenchymal stem cells modulated inflammatory biomarkers by decreasing CXCL12 and increasing IL-10 expression in a DHT-induced androgenic alopecia mouse model, indicating potential for treating hair loss through immunoregulation.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

This study found that activin affects both stromal cells and keratinocytes in skin morphogenesis and repair, with dose-dependent effects on keratinocytes demonstrated through transgenic mouse models.

This study found that GPC1 is a key regulator of angiogenesis in human dermal microvascular endothelial cells, influenced by factors secreted by keratinocytes, and may be a target for alopecia treatment research.

This study identified a novel class of nonsteroidal ligands that can mimic the effects of dihydrotestosterone on androgen receptors, suggesting potential therapeutic applications in male fertility and hormone replacement therapy.

This study found that inhibiting the gp130 Y814 signaling module promotes tissue regeneration and may prevent pathological outcomes after injury in animal models.

This study in mice found that a monoclonal antibody targeting EGFR resulted in skin inflammation mediated by TNFα, suggesting potential pathways for addressing EGFR antibody-induced skin rash in cancer patients.

This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.

This study explored the genetic regulation of goose feather follicle development, identifying miR-200a as a key regulator that inhibits GEDF proliferation through the Wnt pathway, potentially impacting goose down quality and supporting selective breeding strategies.

In this research, LEF1 was identified as a crucial transcription factor for submucosal gland development in mouse and ferret tracheas, though it requires other factors to induce gland formation.

This study found that androgens decreased splenic macrophage FcgammaR expression and impaired the clearance of IgG-coated cells in an experimental guinea pig model.

This study found that endothelin-1 increases adhesion and chemotaxis of amelanotic melanocytes on fibronectin, laminin, and collagen IV, potentially through changes in the actin cytoskeleton.

This review discusses the roles of androgens in female mammals, focusing on how androgen receptor activity in pig reproductive organs may influence ovulation rate and litter size, but reports no new experimental results.

This study found that transgenic mice overexpressing the BMP antagonist noggin showed increased hair follicle size and altered hair type, linked to changes in cell proliferation and gene expression.

This study identifies SOX9 as a critical downstream effector of ERG in TMPRSS2:ERG fusion-positive prostate cancer, indicating its role in tumor invasion and growth.

This study found that irisin, a myokine, increases hair growth by activating the Wnt/β-catenin pathway, enhancing cell proliferation and hair shaft elongation in both human cell and mouse models.

In this study, enteroendocrine cells were shown to coordinate intestinal stem cell migration towards a wound in Drosophila by releasing a ligand that activates non-canonical Wnt signaling, aiding efficient tissue repair.

This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.

This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.

In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.

This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hair loss, suggesting potential therapeutic use.

This study shows that the concentration of epidermal growth factor (EGF) is crucial for determining whether mink hair follicles are promoted or inhibited in vitro, with involvement of the Notch signaling pathway in DP cell proliferation.

This study found that aminoguanidine induced increased VEGF mRNA expression in stored hair follicle micrografts, suggesting potential for developing growth-promoting storage solutions in hair restoration surgery.

In this study, researchers observed that the sebaceous gland niche in mice allows for Wnt-induced hair follicle differentiation, unlike the non-permissive bulge.

This study found that incorporating cell-adhesive ligands into 3D peptide hydrogels supports the survival and osteogenic differentiation of human amniotic mesenchymal stem cells.

In this study, transgenic mice altered to express a Clim-inhibiting molecule under a keratin promoter showed corneal degradation and hair follicle failure, highlighting Clim proteins' role in maintaining these tissues.