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Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Microsechium helleri extract has antioxidant, anti-inflammatory, antidiabetic, and heart-protective benefits.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Teak seed extract is safe and reduces pain in mice.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Early NAS level changes affect alcohol consumption vulnerability.

Transplant patients often get skin problems, with treatments varying by condition.

The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.

SM04755 may be an effective topical treatment for psoriasis.

SIG-1451 could be a promising new treatment for atopic dermatitis.

Fisetin may help treat psoriasis and reduce skin inflammation.

SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.

The model and estimator can predict drug exposure in kidney transplant patients well.