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Genetics and hormones cause hair loss; finasteride treats it safely.

Chromosomal differences affect how muscle cells respond to testosterone.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

The document concludes that effectively managing PCOS requires a multifaceted approach.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Finasteride can cause sexual problems and depression in young men.