43 citations
,
November 2019 in “American Journal of Clinical Dermatology” This review discusses female androgenetic alopecia, highlighting its diagnostic challenges and management strategies, but it reports no new results.
36 citations
,
May 2021 in “Nutrients” This review summarizes current knowledge on the efficacy of natural molecule supplementation, such as inositols and omega-3 fatty acids, in managing PCOS symptoms but reports no new clinical results.
March 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study found that female patients with acne had significantly higher insulin resistance compared to a control group without acne, suggesting that acne could serve as an early clinical marker of insulin resistance in women of reproductive age.
December 2023 in “Research in pharmacy” This review underscores the importance of phytotherapeutic compounds and adjuncts in managing polycystic ovarian syndrome but does not present new clinical evidence.
991 citations
,
January 2011 in “Nature Reviews Endocrinology” This paper reviews the diagnostic criteria, associated morbidities, and possible evolutionary advantages of polycystic ovary syndrome, but does not report any new findings.
89 citations
,
November 2014 in “Medical Clinics of North America” This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.
41 citations
,
June 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
21 citations
,
January 2020 in “General and Comparative Endocrinology” This review examines the diverse roles of SRD5α enzymes across species, focusing on their involvement in steroid synthesis, sexual development, and various physiological processes, but reports no new clinical results.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” In this study, isotretinoin treatment in women with severe acne increased body weight and triglycerides but did not affect androgens or insulin sensitivity.
16 citations
,
March 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne was the most common dermatological manifestation in Korean women with polycystic ovary syndrome, particularly those with a specific combination of symptoms, showing distinct variations in serum hormonal and metabolic parameters.
14 citations
,
January 2019 in “Skin appendage disorders” This paper discusses the first reported case of post-finasteride syndrome in a long-term dermatotrichology setting, occurring in a 25-year-old male after dutasteride treatment, and highlights possible links to mental health disorders.
8 citations
,
September 2024 in “Portuguese Journal of Dermatology and Venereology” This review discusses the role of dermatologists in diagnosing and treating PCOS-related dermatological manifestations, emphasizing the importance of early intervention to enhance patients' quality of life, but reports no new clinical findings.
3 citations
,
November 2022 in “Baghdad Journal of Biochemistry and Applied Biological Sciences” This study found that renin and d-dimer levels were significantly higher in PCOS patients, particularly those also infected with COVID-19, compared to non-PCOS women.
3 citations
,
February 2018 in “InTech eBooks” This chapter discusses the current developments in Traditional Chinese Medicine for treating PCOS but reports no new clinical results, emphasizing the need for further research in this area.
2 citations
,
April 2015 in “Journal of Evolution of Medical and Dental Sciences” This study found that patients with hypothyroidism at a tertiary hospital in South India most commonly exhibited skin dryness (xerosis/ichthyosis) and swelling of the feet (pedal oedema).
1 citations
,
October 2022 in “International journal of endocrinology” This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.
This review discusses various management methods for adolescents with PCOS, highlighting lifestyle modifications and pharmaceuticals like metformin and oral contraceptives, but reports no new clinical results; the authors emphasize individualized treatment plans.
February 2024 in “Brazilian Journal of Implantology and Health Sciences” This review discusses the high prevalence of dermatological manifestations like hirsutism and acne in PCOS patients and explores various therapeutic approaches, highlighting the need for early recognition and treatment.
This study found that most participants had limited awareness of PCOS and its major risk factors, underscoring a need for increased education on the condition.
February 2021 in “International Journal of Science and Research (IJSR)” This study found that the total testosterone/dihydrotestosterone ratio is significantly higher in women with polycystic ovary syndrome and is associated with a worse metabolic profile in both PCOS and healthy women.
75 citations
,
November 1996 in “Fertility and Sterility” This study found that finasteride effectively reduced hirsutism in women during 12 months of treatment, with some effects persisting in the majority after stopping the medication.
12 citations
,
August 2011 in “European Journal of Endocrinology” This study found that anti-Müllerian hormone (AMH) is a valuable primary variable for classifying functional androgenization, especially in distinguishing ovarian-related groups, and supports the novel stratification system.
4025 citations
,
December 2003 in “Human Reproduction” This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.
75 citations
,
June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
60 citations
,
February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
24 citations
,
October 1994 in “Fertility and Sterility” This study suggests that in women with androgenic alopecia and men with premature balding, enhanced 5α-reductase activity and altered androgen conjugation, favoring sulfurylation, may be involved in scalp hair loss.
13 citations
,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
12 citations
,
May 1995 in “Australasian Journal of Dermatology” This review reports that while anti-androgen therapy can improve hair loss in up to 50% of women with androgenetic alopecia, it typically only slows the rate of loss rather than promoting new growth.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.
August 2015 in “Postgraduate obstetrics & gynecology” This article discusses the unapproved use of metformin for treating polycystic ovary syndrome; it provides educational content for physicians but reports no new clinical results.