Nail Changes in Patients with Graft-Versus-Host Disease
February 2011
Studysummary This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women, affecting nearly 60% of participants. Our plain-language summary of this paper — not a Tressless recommendation.
The document reports a study analyzing nail changes in 31 patients with graft-versus-host disease (GVHD) out of 138 patients observed for one year. The study found that the most common nail change was the longitudinal ridge, followed by Beau line, onychomadesis, paronychia, trachyonychia, onycholysis, and leukonychia. Severe nail changes like onychatrophy and pterygium were rare. The study concluded that nail changes in GVHD are more likely related to the nail matrix rather than the nail bed and that there is little correlation between the presence or absence of nail changes and the severity of skin GVHD. No commercial support was identified for this study.