August 2015 in “Postgraduate obstetrics & gynecology” This article discusses the unapproved use of metformin for treating polycystic ovary syndrome; it provides educational content for physicians but reports no new clinical results.
114 citations
,
March 2018 in “PLOS Medicine” This study found that women with polycystic ovary syndrome have higher rates of nonalcoholic fatty liver disease, with androgen excess contributing to the risk.
41 citations
,
June 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.
16 citations
,
April 2018 in “Current opinion in gynecology and obstetrics” The study observed that Hispanic women with PCOS had significantly higher odds of having NASH compared to non-Hispanic women, suggesting routine screening may be beneficial in this high-risk group.
15 citations
,
December 2016 in “Revista Da Associacao Medica Brasileira” This review examines the literature on polycystic ovary syndrome, focusing on its pathogenesis, diagnosis, and links to cardiovascular and hypertensive disorders, but presents no new clinical findings.
15 citations
,
October 2010 in “Archives of Toxicology” This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.
13 citations
,
November 2024 in “BMC Psychiatry” This study found that women with PCOS have a high prevalence of depression and anxiety, with poor mental well-being linked to both conditions, suggesting the need for mental health screening in these patients.
13 citations
,
January 2024 in “Cureus” This study reviewed the physiological and psychological impacts of acne vulgaris, highlighting its complex interactions with endocrine issues, sebum production, and immune response, while suggesting that a multidisciplinary approach can inform future treatments and improve quality of life for those affected.
11 citations
,
March 2008 in “Experimental Dermatology” This study identified a thiazolidine dione derivative as a potential inhibitor of 15-PGDH that may enhance prostaglandin activity in hair follicles, suggesting its use to support hair regrowth treatments.
9 citations
,
January 2015 in “Springer eBooks” This article reviews the diagnostic criteria and management strategies for polycystic ovary syndrome but reports no new clinical findings; it highlights associated health risks and recommended treatments.
7 citations
,
July 2025 in “International Journal of Dermatology” This meta-analysis found that patients with alopecia areata have significantly higher odds of also having immune-mediated diseases such as atopic dermatitis, autoimmune thyroiditis, inflammatory bowel disease, systemic lupus erythematosus, and vitiligo, suggesting a need for comprehensive screening and interdisciplinary management.
4 citations
,
September 2024 in “The Egyptian Journal of Internal Medicine” This review highlights that obesity is linked to various hormonal imbalances beyond diabetes, prompting attention to related endocrine disorders in obese patients, including their prevalence, clinical presentation, and treatment considerations.
4 citations
,
January 2019 in “Clinical Chemistry” This article discusses the complexities of diagnosing PCOS and highlights the importance of early recognition and treatment to improve patient outcomes, despite often being overlooked.
1 citations
,
January 2022 in “Saudi journal of medicine” This systematic review found that PCOS is a leading cause of anovulatory infertility, accounting for 70% of such cases, and emphasized the importance of using ultrasound for diagnosis.
This chapter reviews current and future strategies for identifying ligands and functions of orphan G protein-coupled receptors, but it reports no new experimental results.
January 2022 in “Springer eBooks” The book explains causes and treatments for common hair loss, its psychological effects, related health risks, and emphasizes early screening and lifestyle changes.
52 citations
,
February 2018 in “Diabetology & Metabolic Syndrome” This review discusses the association between various skin conditions and metabolic syndrome, reporting no new clinical results but suggesting a potential reciprocal relationship that warrants further investigation.
33 citations
,
September 2008 in “Dermatologic therapy” This review describes the clinical evaluation and management options for women with polycystic ovary syndrome, focusing on its endocrine and metabolic implications, but reports no new results.
30 citations
,
September 2017 in “Clinics in Dermatology” This article reviews the clinical and histological features of acanthosis nigricans and its associations with insulin resistance and other conditions, but highlights the need for more research on its classification, severity assessment, and treatment options.
30 citations
,
September 2017 in “Clinics in Dermatology” This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.
23 citations
,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
17 citations
,
November 2000 in “Journal of the American Pharmaceutical Association” This review discusses the perimenopause, its symptoms, and management options, emphasizing the role of pharmacists in educating and advising women on treatment strategies and preventive health measures, but it reports no new results.
14 citations
,
January 2012 in “Endocrine development” This article reviews the challenges in diagnosing mild hyperandrogenism in adolescent girls, discussing potential causes like PCOS and treatment options, but reports no new clinical results.
1 citations
,
March 2011 in “Informa Healthcare eBooks” Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
3 citations
,
June 2023 in “European heart journal open” This study found that oligo-amenorrhea/menstrual irregularity in women is associated with an increased risk of overall cardiovascular disease, coronary heart disease, and myocardial infarction, while evidence linking hyperandrogenism or polycystic ovaries to cardiovascular disease remains mixed or unexplored.
883 citations
,
August 2016 in “Nature Reviews Disease Primers” This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.
286 citations
,
January 2009 in “Human Reproduction Update” This study reports that NIH PCOS is linked to more severe metabolic issues, including higher obesity and insulin resistance, compared to non-NIH PCOS phenotypes.
247 citations
,
August 2011 in “European Journal of Epidemiology” This article outlines the rationale, design, major findings, and updated objectives of the ongoing Rotterdam Study, without presenting new research data.
54 citations
,
May 1998 in “Urology” This study demonstrates that patients with benign prostatic hyperplasia have a higher severity and frequency of male pattern baldness compared to a control group.
38 citations
,
October 2006 in “Fertility and Sterility” The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.