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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Finasteride effectively treats frontal hair loss with few side effects.

Some medicinal plants can help heal wounds and may lead to new treatments.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

Fat cells in the skin help start healing and form important repair cells after injury.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Liposomes could improve how skin care products work but are costly and not very stable.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.